Novel human kinases and polynucleotides encoding the same
Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
1 . An isolated nucleic acid molecule that encodes the amino acid sequence of SEQ ID NO:2, 4, 6, 8, 10, 12, 15, 17, 19, 22, 25, 27, 29, 31, 33, 35, 37, 39, 41, 43, 45, 47, 49, 51, 53, 55, 57, 59, 61, 63, 65, 67, 69, 71, 75, 77, 80, 83, 85, 87, 89, 92, 94, 96, 98, 100, 102, 104, 106, 108, 110, 112, 114, 116, 118, 120, 122, 124, 126, 128, 130, 132, 134, 136, 138, 140, 142, 144, 146, 148, 150, 152, 154, 156, 158, 161, 163, 165, 167, 169, 172, 174, 177, 179, 181, 183, 186, 188, 191, 194, 196, 198, 200, 202, 204, 206, 208, 210, 212, 214, 216, 218, 220, 222, 224, 226, 228, 230, 232, 234, 236, 238, 240, 242, 244, 246, 249, 251, 253, 255, 257, 259, 261, 263, 265, 267, 269, 271, 273, 275, or 278.
2 . The isolated nucleic acid molecule of claim 1 , wherein said nucleic acid molecule comprises the nucleotide sequence of SEQ ID NO:1, 3, 5, 7, 9, 11, 14, 16, 18, 21, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44, 46, 48, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 74, 76, 79, 82, 84, 86, 88, 91, 93, 95, 97, 99, 101, 103, 105, 107, 109, 111, 113, 115, 117, 119, 121, 123, 125, 127, 129, 131, 133, 135, 137, 139, 141, 143, 145, 147, 149, 151, 153, 155, 157, 160, 162, 164, 166, 168, 171, 173, 176, 178, 180, 182, 185, 187, 190, 193, 195, 197, 199, 201, 203, 205, 207, 209, 211, 213, 215, 217, 219, 221, 223, 225, 227, 229, 231, 233, 235, 237, 239, 241, 243, 245, 248, 250, 252, 254, 256, 258, 260, 262, 264, 266, 268, 270, 272, 274, or 277.
3 . An expression vector comprising the isolated nucleic acid molecule of claim 1 .
4 . (canceled)
5 . An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:2, 4, 6, 8, 10, 12, 15, 17, 19, 22, 25, 27, 29, 31, 33, 35, 37, 39, 41, 43, 45, 47, 49, 51, 53, 55, 57, 59, 61, 63, 65, 67, 69, 71, 75, 77, 80, 83, 85, 87, 89, 92, 94, 96, 98, 100, 102, 104, 106, 108, 110, 112, 114, 116, 118, 120, 122, 124, 126, 128, 130, 132, 134, 136, 138, 140, 142, 144, 146, 148, 150, 152, 154, 156, 158, 161, 163, 165, 167, 169, 172, 174, 177, 179, 181, 183, 186, 188, 191, 194, 196, 198, 200, 202, 204, 206, 208, 210, 212, 214, 216, 218, 220, 222, 224, 226, 228, 230, 253, 255, 257, 259, 261, 263, 265, 267, 269, 271, 273, 275, or 278.