Granted Patent
B2
US 7,495,103 · App. 11/165,818 · Granted Feb 24, 2009
Modulators of ATP-binding cassette transporters
Assignee:
Vertex Pharmaceuticals Incorporated
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Abstract
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Claims (4)
1. A compound:
N-(5-hydroxy-2,4-ditert-butyl-phenyl)-4-oxo-1H-quinoline-3-carboxamide,
or a pharmaceutically acceptable salt thereof.
2. A pharmaceutical composition comprising a compound according to claim 1 and a pharmaceutically acceptable carrier or adjuvant.
Assignments (4)
RELEASE OF SECURITY INTEREST
Recorded Oct 14, 2016
From: MACQUARIE US TRADING LLC
To: VERTEX PHARMACEUTICALS INCORPORATED; VERTEX PHARMACEUTICALS (SAN DIEGO) LLC
Reel/Frame 040357/0001 →
ASSIGNEE CHANGE OF ADDRESS
Recorded Jan 26, 2016
From: VERTEX PHARMACEUTICALS INCORPORATED
To: VERTEX PHARMACEUTICALS INCORPORATED
Reel/Frame 037592/0426 →
SECURITY INTEREST
Recorded Jul 10, 2014
From: VERTEX PHARMACEUTICALS INCORPORATED; VERTEX PHARMACEUTICALS (SAN DIEGO) LLC
To: MACQUARIE US TRADING LLC
Reel/Frame 033292/0311 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Dec 21, 2005
From: HADIDA-RUAH, SARA; HAZELWOOD, ANNA; GROOTENHUIS, PETER; GOOR, FRED VAN; SINGH, ASHVANL; ZHOU, JINGLAN; MCCARTNEY, JASON
To: VERTEX PHARMACEUTICALS INCORPORATED
Reel/Frame 017138/0013 →
Continuity (6)
Provisional Application
6058267600
· Jun 24, 2004
Provisional Application
6063012700
· Nov 22, 2004
Provisional Application
6063567400
· Dec 13, 2004
Provisional Application
6065821900
· Mar 3, 2005
Provisional Application
6066131100
· Mar 11, 2005