Method for the treatment of acne

1. A method of treating acne vulgaris, comprising administering to a patient suffering from acne vulgaris an amount of a continuous slow release oral dosage form based on body weight of the patient, said continuous slow release oral dosage form comprising:

an amount of an oral minocycline antibiotic that provides the patient, upon administration once daily without a loading dose, with 0.7 mg/kg/day to 1.3 mg/kg/day of said oral minocycline antibiotic; and

a delivery vehicle having a first lactose monohydrate, a second lactose monohydrate, and a slow dissolving carrier, wherein said first lactose monohydrate is encapsulated by said slow dissolving carrier, wherein said second lactose monohydrate and said slow dissolving carrier are present at a weight ratio of about 0.3 to about 0.5,

wherein said delivery vehicle releases said oral minocycline antibiotic at a release rate of:

A) about 25 to about 52% within about 1 hour about 53 to about 89% within about 2 hours, and at least about 90% within about 4 hours; or

B) about 30 to about 52% within about 1 hour about 53 to about 84% within about 2 hours, and at least about 85% within about 4 hours,

wherein said release rate is measured in an aqueous physiological medium.

2. The method of claim 1 , wherein said amount of 0.7 mg/kg/day to 1.3 mg/kg/day of said oral minocycline antibiotic is about 1 mg/kg/day.

3. The method of claim 1 , wherein said delivery vehicle releases said oral minocycline antibiotic in such a manner that said oral minocycline antibiotic reaches the C max in the person's blood from about 3.5 hours after administration.

4. The method of claim 1 , wherein said second lactose monohydrate and said slow dissolving carrier are present at a weight ratio of about 0.36 to about 0.40.

5. A method of treating acne vulgaris, comprising

administering to a patient suffering from acne vulgaris an amount of a continuous slow release oral dosage form based on body weight of the patient, the continuous slow release dosage form comprising:

an amount of an oral minocycline antibiotic that provides the patient, upon administration once daily without a loading dose, with 0.7 mg/kg/day to 1.3 mg/kg/day of said oral minocycline antibiotic; and

a delivery vehicle having a fast dissolving carrier and a slow dissolving carrier, wherein the fast dissolving carrier has a first portion thereof that is encapsulated by the slow dissolving carrier and a second portion thereof that is not encapsulated by the slow dissolving carrier, and wherein the second portion of the fast dissolving carrier and the slow dissolving carrier are present at a weight ratio of 0.3 to 0.5, wherein the delivery vehicle releases said oral minocycline antibiotic at a release rate of:

A) about 25 to about 52% within about 1 hour about 53to about 89% within about 2 hours, and at leastabout 90% within about 4 hours; or

B) about 30 to about 52% within about 1 hour about 53 to about 84% within about 2 hours, and at leastabout 85% within about 4 hours,

wherein the release rate is measured in an aqueous physiological medium.

6. The method of claim 1 , wherein said slow dissolving carrier is hydroxypropyl methylcellulose.