IP Library Granted Patent US 7,362,848
Granted Patent B2
US 7,362,848 · App. 11/168,613 · Granted Apr 22, 2008

Method for automatic anatomy-specific treatment planning protocols based on historical integration of previously accepted plans

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Quick Facts
Patent No.
US 7,362,848
App. No.
11/168,613
Granted
Apr 22, 2008
Kind
B2
Abstract

A method of automatically optimizing an inverse treatment plan by referencing data from accepted plan libraries.

Claims (52)

1. A method, comprising:

generating a current dose volume histogram for a volume of interest during a radiation treatment planning process, the current dose volume histogram based on a parameter for a treatment planning constraint; and

adjusting automatically the treatment constraint to conform the current dose volume histogram with an accepted dose volume histogram from a plan library.

2. The method of claim 1 , wherein generating further comprises calculating a dose volume histogram for a target region and a dose volume histogram for a critical region.

3. The method of claim 2 , wherein adjusting further comprises comparing the dose volume histogram for the target region with an accepted dose volume histogram from the plan library corresponding to a volume of interest that includes the target region.

4. The method of claim 2 , wherein adjusting further comprises comparing the dose volume histogram for the critical region with an accepted dose volume histogram from the plan library corresponding to a volume of interest that includes the critical region.

5. The method of claim 2 , wherein generating further comprises contouring a pathological anatomy and a critical structure visualized on a display screen.

6. The method of claim 1 , wherein adjusting further comprises determining a deviation between the current dose volume histogram and the accepted dose volume histogram.

7. The method of claim 1 , wherein the parameter comprises a beam weight and adjusting further comprises modifying the beam weight.

8. The method of claim 7 , wherein modifying further comprises incrementally increasing the beam weight until the current dose volume histogram closely matches the accepted dose volume histogram.

9. The method of claim 7 , wherein modifying further comprises incrementally decreasing the beam weight until the current dose volume histogram closely matches the accepted dose volume histogram.

10. The method of claim 1 , wherein generating further comprises contouring a pathological anatomy to identify a target region and contouring a critical structure to identify a critical region.

11. The method of claim 1 , wherein generating further comprises:

generating a current conformality index for the volume of interest; and

adjusting automatically the treatment constraint to conform the current conformality index with an accepted conformality index from the plan library.

12. The method of claim 1 , wherein the radiation treatment planning process comprises inverse planning.

13. A method, comprising:

generating a first contour around a pathological anatomy, within a volume of interest, to identify a target region and a second contour around a critical structure to identify a critical region;

assigning a first beam weight associated with a first radiation beam directed towards the target region;

generating a current dose volume histogram for the critical region based on the first beam weight; and

adjusting automatically the first beam weight to conform the current dose volume histogram for the critical region to a dose volume histogram from a plan library.

14. The method of claim 13 , wherein adjusting further comprises deriving the dose volume histogram from the plan library from a plurality of accepted plans.

15. The method of claim 14 , wherein adjusting further comprises calculating a deviation between the current dose volume histogram for the critical region and the dose volume histogram from the plan library.

16. The method of claim 15 , wherein adjusting further comprises modifying the first beam weight to a second beam weight.

17. The method of claim 16 , wherein modifying further comprises incrementally increasing the first beam weight to the second beam weight until the current dose volume histogram closely matches the dose volume histogram from the plan library.

18. The method of claim 16 , wherein modifying further comprises incrementally decreasing the first beam weight to the second beam weight until the current dose volume histogram closely matches the dose volume histogram from the plan library.

19. The method of claim 14 , wherein deriving further comprises calculating a mean value from a plurality of accepted plans.

20. The method of claim 13 , wherein generating the current dose volume histogram for the critical region further comprises generating a current dose volume histogram for the target region.

21. The method of claim 20 , wherein adjusting further comprises calculating a deviation between the current dose volume histogram for the target region and the dose volume histogram from the plan library.

22. The method of claim 21 , wherein adjusting further comprises modifying the first beam weight to a second beam weight.

23. The method of claim 22 , wherein modifying further comprises incrementally increasing the first beam weight to the second beam weight until the current dose volume histogram closely matches the dose volume histogram from the plan library.

24. The method of claim 22 , wherein modifying further comprises incrementally decreasing the first beam weight to the second beam weight until the current dose volume histogram closely matches the dose volume histogram from the plan library.

25. An apparatus, comprising:

means for generating a current dose volume histogram for a volume of interest during inverse planning based on a parameter for a treatment planning constraint; and

means for adjusting automatically the treatment constraint to conform the current dose volume histogram with an accepted dose volume histogram from a plan library.

26. The apparatus of claim 25 , wherein means for adjusting further comprises means for comparing a current dose volume histogram for a target region with an accepted dose volume histogram from the plan library corresponding to a volume of interest that includes the target region.

27. The apparatus of claim 25 , wherein means for adjusting further comprises means for comparing a dose volume histogram for a critical region with an accepted dose volume histogram from the plan library corresponding to a volume of interest that includes the critical region.

28. The apparatus of claim 25 , wherein means for adjusting further comprises means for determining a deviation between the current dose volume histogram and the accepted dose volume histogram.

29. The apparatus of claim 25 , wherein the parameter comprises a beam weight and means for adjusting further comprises means for modifying the beam weight.

30. An apparatus, comprising:

a database to store a plan library comprising an accepted dose volume histogram; and

a processor coupled to the database to compare the accepted dose volume histogram with a current dose volume histogram and automatically adjust a parameter for a treatment planning constraint to conform the current dose volume histogram with the accepted dose volume histogram.

31. The apparatus of claim 30 , further comprising a memory coupled to the processor, the memory to store the accepted dose volume histogram and the current dose volume histogram during a comparison.

32. The apparatus of claim 30 , wherein the processor is configured to calculate a deviation of the current dose volume histogram with respect to the accepted dose volume histogram.

33. The apparatus of claim 30 , wherein the parameter comprises a radiation beam weight.

34. A machine readable medium having instructions thereon, which when executed by a processor, cause the processor to perform the following comprising:

generating a current dose volume histogram for a volume of interest during a radiation treatment planning process, the current dose volume histogram based on a parameter for a treatment planning constraint; and

adjusting automatically the treatment constraint to conform the current dose volume histogram with an accepted dose volume histogram from a plan library.

35. The machine readable medium of claim 34 , wherein adjusting further comprises comparing a current dose volume histogram for a target region with an accepted dose volume histogram from the plan library corresponding to a volume of interest that includes the target region.

36. The machine readable medium of claim 34 , wherein adjusting further comprises comparing a current dose volume histogram for a critical region with an accepted dose volume histogram from the plan library corresponding to a volume of interest that includes the critical region.

37. The machine readable medium of claim 34 , wherein adjusting further comprises determining a deviation between the current dose volume histogram and the accepted dose volume histogram.

38. The machine readable medium of claim 34 , wherein the parameter comprises a beam weight and adjusting further comprises modifying the beam weight.

Assignments (12)
GRANT OF A SECURITY INTEREST - PATENTS Recorded Nov 7, 2025
From: ACCURAY LLC
To: TCW ASSET MANAGEMENT COMPANY LLC, AS COLLATERAL AGENT
Reel/Frame 073575/0358 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 13, 2025
From: ACCURAY INCORPORATED
To: ACCURAY LLC
Reel/Frame 072421/0584 →
RELEASE OF SECURITY INTEREST Recorded Jun 6, 2025
From: FIRST-CITIZENS BANK & TRUST COMPANY
To: ACCURAY INCORPORATED
Reel/Frame 071638/0034 →
RELEASE OF SECURITY INTEREST Recorded May 20, 2021
From: MIDCAP FINANCIAL TRUST
To: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
Reel/Frame 056318/0751 →
RELEASE OF SECURITY INTEREST Recorded May 20, 2021
From: MIDCAP FUNDING IV TRUST (AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FUNDING X TRUST, AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FUNDING IV TRUST, AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FINANCIAL TRUST)
To: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
Reel/Frame 056318/0559 →
SECURITY INTEREST Recorded May 14, 2021
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: SILICON VALLEY BANK, AS ADMINISTRATIVE AND COLLATERAL AGENT
Reel/Frame 056247/0001 →
ASSIGNMENT OF SECURITY AGREEMENTS Recorded Mar 1, 2019
From: MIDCAP FUNDING X TRUST (AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FUNDING IV TRUST, AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FINANCIAL TRUST), AS EXISTING ADMINISTRATIVE AGENT
To: MIDCAP FUNDING IV TRUST, AS SUCCESSOR TO EXISTING ADMINISTRATIVE AGENT
Reel/Frame 048481/0804 →
SECURITY INTEREST Recorded Dec 19, 2017
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: MIDCAP FINANCIAL TRUST
Reel/Frame 044910/0685 →
RELEASE OF SECURITY INTEREST Recorded Jun 15, 2017
From: CERBERUS BUSINESS FINANCE, LLC. AS COLLATERAL AGENT
To: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
Reel/Frame 042821/0580 →
SECURITY INTEREST Recorded Jun 15, 2017
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: MIDCAP FUNDING IV TRUST (AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FINANCIAL TRUST)
Reel/Frame 042826/0358 →
ASSIGNMENT FOR SECURITY - PATENTS Recorded Jan 13, 2016
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: CERBERUS BUSINESS FINANCE, LLC, AS COLLATERAL AGENT
Reel/Frame 037513/0170 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 27, 2005
From: SARACEN, MICHAEL J.; WEST, JAY B.
To: ACCURAY INCORPORATED
Reel/Frame 016737/0825 →