Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols
The present invention is directed to soft gel compositions, methods of delivery and packaged nutraceuticals of the soft gel compositions that include at least one polymethoxylated flavone and, optionally, at least one tocotrienol. Optional active ingredients include a phytosterol, DHA, EPA, coenzyme Q-10 or an analog thereof and mixtures thereof.
1. A soft gelatin capsule for maintaining cardiovascular health comprising effective amounts of:
nobiletin and tangeretin in about a 1:1, v:v ratio;
tocotrienol, wherein the tocotrienol is derived from palm oil;
at least one of a phytosterol, docosahexaenoic acid, Eicosapentanoic acid, coenzyme Q-10 or an analog thereof, polycosinol, red yeast rice, gugulipid, pantethine, garlic, chromium, carnitine, artichoke leaf, green tea, Gymnema sylvestre , grape seed extract, pine bark extract, ginseng, silymarin or mixtures thereof; and
an oil carrier.
2. The soft gelatin capsule of claim 1 , wherein the tocotrienol is a mixture of tocotrienols.
3. The soft gelatin capsule of claim 1 , wherein the oil carrier is olive or rice bran oil.
4. The soft gelatin capsule of claim 3 , further comprising a monoterpene.
5. The soft gelatin capsule of claim 4 , wherein the monoterpene is limonene.
6. The soft gelatin capsule of claim 4 , further comprising titanium dioxide.
7. The soft gelatin capsule of claim 6 , further comprising chlorophylline.
8. The soft gelatin capsule of claim 7 , further comprising riboflavin.
9. The soft gelatin capsule of claim 2 , wherein the oil carrier is olive or rice bran oil.
10. The soft gelatin capsule of claim 9 , further comprising a monoterpene.
11. The soft gelatin capsule of claim 10 , wherein the monoterpene is limonene.
12. The soft gelatin capsule of claim 10 , further comprising titanium dioxide.
13. The soft gelatin capsule of claim 12 , further comprising chlorophylline.
14. The soft gelatin capsule of claim 13 , further comprising riboflavin.
15. The soft gelatin capsule of claim 1 , further comprising cholestyramine, colestipol, clofibrate, colesevelam, gemfibrozil, niacin, fenofibrate, Ezetimibe, Lovastatin, Simvastatin, Pravastatin, Fluvastatin, Rosuvastatin Calcium, Atorvastatin or combinations thereof.
16. A packaged nutraceutical composition comprising the soft gelatin capsules according to claim 1 .
17. A soft gelatin capsule comprising:
nobiletin and tangeretin in about a 1:1, v:v ratio;
a tocotrienol, wherein the tocotrienol is derived from palm oil;
at least one of a phytosterol, docosahexaenoic acid, Eicosapentanoic acid, coenzyme Q-10 or an analog thereof, polycosinol, red yeast rice, gugulipid, pantethine, garlic, chromium, carnitine, artichoke leaf, green tea, Gymnema sylvestre, grape seed extract, pine bark extract, ginseng, silymarin or mixtures thereof; and
an oil carrier;
wherein the capsule includes from about 5 to about 40 weight percent of the nobiletin and tangeretin and the tocotrienol.
18. The soft gelatin capsule of claim 17 , wherein the capsule includes from about 10 to about 30 weight percent of the nobiletin and tangeretin and the tocotrienol.