Cyclosporin compositions
Cyclosporin A compositions are disclosed herein comprising an oil and a surfactant.
1 . A composition comprising cyclosporin A, an oil, and a stearate surfactant, wherein said composition is an ophthalmically acceptable emulsion.
2 . The composition of claim 1 comprising Almond oil.
3 . The composition of claim 1 comprising Corn oil.
4 . The composition of claim 1 comprising Arachis oil.
5 . The composition of claim 1 comprising Cottonseed oil.
6 . The composition of claim 1 comprising Safflower oil.
7 . The composition of claim 1 comprising Maize oil.
8 . The composition of claim 1 comprising Linseed oil.
9 . The composition of claim 1 comprising Rapeseed oil.
10 . The composition of claim 1 comprising Soybean oil.
11 . The composition of claim 1 comprising Olive oil.
12 . The composition of claim 1 comprising Caraway oil.
13 . The composition of claim 1 comprising Rosemary oil.
14 . The composition of claim 1 comprising Peanut oil.
15 . The composition of claim 1 comprising Peppermint oil.
16 . The composition of claim 1 comprising Sunflower oil.
17 . The composition of claim 1 comprising Eucalyptus oil.
18 . The composition of claim 1 comprising Sesame oil.
19 . A composition comprising cyclosporin A, an oil having a specific gravity below 0.9, wherein said composition is an ophthalmically acceptable emulsion.
20 . The composition of claim 1 comprising Mineral oil.
21 . The composition of claim 1 comprising a POE (40) monostearate surfactant.
22 . The composition of claim 21 having from about 0.001% to about 0.1% cyclosporin A.
23 . The composition of claim 22 having from about 0.005% to about 0.05% cyclosporin A.
24 . The composition of claim 23 having about 0.05% cyclosporin A.