IP Library Granted Patent US 7,738,683
Granted Patent B2
US 7,738,683 · App. 11/187,677 · Granted Jun 15, 2010

Abnormality detection in medical images

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Quick Facts
Patent No.
US 7,738,683
App. No.
11/187,677
Granted
Jun 15, 2010
Kind
B2
Abstract

A system for the detection of abnormalities in a medical image of a subject. The system includes an examination bundle, a learning engine, and a detecting engine. The examination bundle includes at least one medical image of the subject from a first modality and at least one medical image of the subject from a second modality. The learning engine is employed for determining the characteristics of abnormalities within the at least one medical image from the first modality and the at least one medical image from the second modality. The detecting engine is employed for detecting abnormalities within at least one of the medical images comprising the examination bundle.

Claims (25)

1. A system for the detection of abnormalities in a medical image of a subject, comprising:

an examination bundle including at least one medical image of the subject from a first modality and at least one medical image of the subject from at least a second modality;

a mapping engine for defining a correspondence relationship between the at least one medical image from the first modality and the at least one medical image from the at least second modality;

a training/learning engine for determining the characteristics of abnormalities using features extracted within the at least one medical image from the first modality and the at least one medical image from the at least second modality;

a classification engine for detecting abnormalities within at least one of the medical images comprising the examination bundle; and

a combining module combining training/learning processes for determining the characteristics of abnormalities using features extracted from the first and second modalities and the detected abnormalities from the first and second modalities using the classification engine for diagnosis and identifying abnormalities detected in both of the first and second modalities.

2. The system of claim 1 , wherein the training/learning engine registers the at least one medical image from the first modality with the at least one medical image from the second modality.

3. The system of claim 2 , wherein the training/learning engine performs parametric image registration, non-parametric image registration, intensity-based registration, correlation-based registration, or mutual information-based registration.

4. The system of claim 1 , wherein the training/learning engine registers at least one medical image from at least one modality to an atlas image.

5. The system of claim 1 , wherein the training/learning engine comprises (a) a first learning module for determining the characteristics of abnormalities within the at least one medical image from the first modality and (b) a second learning module for determining the characteristics of abnormalities within the at least one medical image from the second modality; and

wherein the classification engine comprises (a) a first detecting module for detecting abnormalities within the at least one medical image from the first modality, and (b) a second detecting module for detecting abnormalities within the at least one medical image from the second modality.

6. The system of claim 5 , wherein at least one of the first or second learning modules incorporates predetermined knowledge of the characteristics of abnormalities.

7. The system of claim 5 , wherein the classification engine further comprises a combining module for combining the detected abnormalities from the first detecting module with the detected abnormalities from the second detecting module.

8. A system for the detection of abnormalities in a medical image of a subject, comprising:

an examination bundle including at least one medical image of the subject from a first modality and at least one medical image of the subject from at least a second modality;

a plurality of trained images employed for determining the characteristics of abnormalities within the at least one medical image from the first modality and the at least one medical image from the at least second modality;

a classification engine for detecting abnormalities within the medical images of the first and second modalities comprising the examination bundle using the characteristics; and

a combining module combining the detected abnormalities for determining the characteristics of abnormalities using features extracted from the first and second modalities and the detected abnormalities of the classification engine for diagnosis and identifying abnormalities detected in both of the first and second modalities.

9. The system of claim 8 , further comprising a mapping engine for defining a correspondence relationship between the at least one medical image from the first modality and the at least one medical image from the second modality.

10. The system of claim 1 , wherein the combining module determines joint characteristics from both the first and second modalities.

11. The system of claim 1 , wherein the combining module identifies all detected abnormalities, identifies abnormalities detected by one modality, identifies abnormalities detected by both modalities and identifies abnormalities detected by a chosen modality.

12. A method, comprising:

determining characteristics of abnormalities in medical images of plural modalities using a training/learning engine;

detecting and classifying abnormalities in the images using a classification engine; and

combining the classified abnormalities and image features of the medical images of the plural modalities for use in computer aided analysis and diagnosis applied to an examination image bundle including patient images in the first and second modalities and one of identifying an abnormality detected in more than one of the plural modalities, and identifying an abnormality detected in a chosen modality and another one of the plural modalities.

Assignments (13)
RELEASE OF SECURITY INTEREST Recorded Oct 14, 2022
From: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
To: CARESTREAM HEALTH, INC.; CARESTREAM DENTAL, LLC; QUANTUM MEDICAL IMAGING, L.L.C.; QUANTUM MEDICAL HOLDINGS, LLC; TROPHY DENTAL INC.
Reel/Frame 061681/0380 →
RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY (FIRST LIEN) Recorded Oct 14, 2022
From: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
To: CARESTREAM HEALTH, INC.; CARESTREAM DENTAL LLC; QUANTUM MEDICAL IMAGING, L.L.C.; TROPHY DENTAL INC.
Reel/Frame 061683/0441 →
RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY (SECOND LIEN) Recorded Oct 14, 2022
From: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
To: CARESTREAM HEALTH, INC.; CARESTREAM DENTAL LLC; QUANTUM MEDICAL IMAGING, L.L.C.; TROPHY DENTAL INC.
Reel/Frame 061683/0601 →
SECOND LIEN INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jul 1, 2013
From: CARESTREAM HEALTH, INC.; CARESTREAM DENTAL LLC; QUANTUM MEDICAL IMAGING, L.L.C.; TROPHY DENTAL INC.
To: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
Reel/Frame 030724/0154 →
AMENDED AND RESTATED INTELLECTUAL PROPERTY SECURITY AGREEMENT (FIRST LIEN) Recorded Jun 28, 2013
From: CARESTREAM HEALTH, INC.; CARESTREAM DENTAL LLC; QUANTUM MEDICAL IMAGING, L.L.C.; TROPHY DENTAL INC.
To: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
Reel/Frame 030711/0648 →
RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY (SECOND LIEN) Recorded Mar 13, 2012
From: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
To: CARESTREAM HEALTH, INC.
Reel/Frame 027851/0812 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded May 12, 2011
From: CARESTREAM HEALTH, INC.; CARESTREAM DENTAL, LLC; QUANTUM MEDICAL IMAGING, L.L.C.; QUANTUM MEDICAL HOLDINGS, LLC; TROPHY DENTAL INC.
To: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
Reel/Frame 026269/0411 →
RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY (FIRST LIEN) Recorded Apr 4, 2011
From: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
To: CARESTREAM HEALTH, INC.
Reel/Frame 026069/0012 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 7, 2008
From: EASTMAN KODAK COMPANY
To: CARESTREAM HEALTH, INC.
Reel/Frame 020741/0126 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 7, 2008
From: EASTMAN KODAK COMPANY
To: CARESTREAM HEALTH, INC.
Reel/Frame 020756/0500 →
FIRST LIEN OF INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jul 27, 2007
From: CARESTREAM HEALTH, INC.
To: CREDIT SUISSE, CAYMAN ISLANDS BRANCH, AS ADMINISTRATIVE AGENT
Reel/Frame 019649/0454 →
SECOND LIEN INTELLECTUAL PROPERTY SECURITY AGREEME Recorded Jul 27, 2007
From: CARESTREAM HEALTH, INC.
To: CREDIT SUISSE, CAYMAN ISLANDS BRANCH, AS ADMINISTRATIVE AGENT
Reel/Frame 019773/0319 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2005
From: CAHILL, NATHAN D.; CHEN, SHOUPU; SUN, ZHAOHUI; RAY, LAWRENCE A.
To: EASTMAN KODAK COMPANY
Reel/Frame 016968/0515 →