Enhanced adipose tissue
View Patent ↗An enhanced adipose tissue containing native adipose tissue and a concentrated amount of an active agent derived from adipose tissue, wherein the enhanced adipose tissue is preferably injected into the intervertebral disc of a patient suffering from degenerative disc disease.
1. A graft derived from adipose tissue comprising a native level of an active agent, comprising:
a) native adipose tissue, and
b) a first active agent derived from adipose tissue and present at a level greater than the native level of the active agent in adipose tissue,
wherein the first active agent is adiponectin.
2. The graft of claim 1 wherein the first active agent is present in the graft at a level greater than 10 μg/ml.
3. The graft of claim 1 wherein the native adipose tissue is minced.
4. The graft of claim 3 wherein the minced tissue is characterized by a bimodal size distribution.
5. The graft of claim 1 further comprising:
c) a scaffold.
6. The graft of claim 1 further comprising:
c) a growth factor.
7. The graft of claim 1 further comprising:
c) a second active agent.