High throughput mechanical alloying and screening
View Patent ↗The invention provides an apparatus and methods for conducting ball milling operations in a high throughput manner. Also provided are devices and methods for high throughput screening of alloys and other materials to identify those that have desired gas storage properties.
1. A multiwell ball milling fixture consisting essentially of a multiwell plate, a cap, at least one seal, and a lid, wherein:
(a) the multiwell plate comprises a plurality of sample wells that comprise a liner, wherein each sample well is formed within the thickness of the multiwall plate so that the top of each sample well opens into the upper surface of the multiwall plate, and further wherein each sample well further comprises a sidewall and a bottom surface, wherein the bottom surface is joined to the sidewall by a rounded edge;
(b) the lid defining a planar expanse sufficient to cover the sample wells, which lid comprises (i) a plurality of recessed areas which have a cross-sectional shape that corresponds to the cross-sectional shape of the sample wells, and the positions of which recessed areas spatially correspond to the sample wells when the lid is placed on the multiwell plate, said recessed area comprise a top surface that is concave relative to the planar expanse of the lid, and (ii) a plurality of gas outlet ports, wherein the gas outlet ports are positioned such that two or more of the sample wells are each in fluid communication with an associated gas outlet port when the lid is positioned on the multiwell plate and the fixture does not include a sizing screen; and
(c) the cap defines a planar expanse sufficient to cover each of the plurality of gas outlet ports when the cap is positioned on the lid,
wherein the sample wells are sealed when the lid and cap are attached to the multiwell plate.
2. The multiwell ball milling fixture of claim 1 , wherein the at least one seal further comprises one or more seals disposed between the multiwell plate and the lid, which seals allow gas flow between a sample well and an associated gas outlet port but prevent gas flow between sample wells and between a sample well and a non-associated gas outlet port.
3. The multiwell ball milling fixture of claim 2 , wherein the seals comprise O-rings.
4. The multiwell ball milling fixture of claim 1 , wherein the at least one seal further comprises one or more seals disposed between the lid and the cap, which seals prevent gas flow from one gas outlet port to a second gas outlet port associated with a second sample well.
5. The multiwell ball milling fixture of claim 1 , wherein the recessed areas have a diameter that is the same as the diameter of the sample wells.
6. The multiwell ball milling fixture of claim 1 , wherein the concave top surface of the recessed areas has a radius of curvature that is identical to the radius of the rounded edge that joins the sidewall and the bottom surface of the multiwell plate.
7. The multiwell ball milling fixture of claim 1 , wherein either or both of the multiwell plate and the lid are constructed of stainless steel.
8. The multiwell ball milling fixture of claim 1 , wherein the sample wells contain an inert gas.
9. The multiwell ball milling fixture of claim 1 , wherein the liner comprises a material selected from the group consisting of stainless steel, carbon steel, tungsten carbide and ceramics.
10. The multiwell ball milling fixture of claim 1 , wherein the lid comprises a plurality of recessed areas which have a cross-sectional shape that corresponds to the cross-sectional shape of the sample wells, and the positions of which spatially correspond to the sample wells when the lid is placed on the multiwell plate.
11. The multiwell ball milling fixture of claim 10 , wherein the recessed areas comprise a top surface that is concave relative to the planar expanse of the lid.