IP Library Granted Patent US 9,480,585
Granted Patent B2
US 9,480,585 · App. 11/222,595 · Granted Nov 1, 2016

Implant of low radial strength

Inventors: Bodo Gerold (Zellingen, DE); Claus Harder (Uttenreuth, DE); Bernd Heublein (Hannover, DE); Heinz Mueller (Erlangen, DE)
Assignee: BIOTRONIK VI PATENT AG
A61F2/86A61L31/022A61F2/90A61F2/91
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Quick Facts
Patent No.
US 9,480,585
App. No.
11/222,595
Granted
Nov 1, 2016
Kind
B2
Abstract

The invention concerns an endovascular implant comprising a biodegradable material and having a tubular main body which is open at the ends and which is dilatable from an unexpanded condition into an expanded condition. The implant is so designed that when the implant in the expanded condition is subjected to a radially acting compression pressure in the range of between 5 and 30 kPa (0.05-0.3 bar) a cross-sectional area of the implant is reduced to 70% or less of the original cross-sectional area, or an internal volume of the implant is reduced to 70% or less of the original internal volume.

Claims (22)

1. An endovascular implant comprising a biodegradable material and having a tubular main body which is open at the ends and which is dilatable from an unexpanded condition into an expanded condition, wherein the implant is so designed that, prior to implantation, when the implant in the expanded condition is subjected to a radially acting compression pressure in the range of between 5 and 30 kPa (0.05-0.3 bar)

a cross-sectional area of the implant is reduced to 70% or less of the original cross-sectional area, or

an internal volume of the implant is reduced to 70% or less of the original internal volume.

2. An implant as set forth in claim 1 , wherein the compression pressure is in the range of between 10 and 20 kPa (between 0.1 and 0.2 bar).

3. An implant as set forth in claim 1 , wherein the implant is formed from a material with a modulus of elasticity of between 10 and 60 GPa.

4. An implant as set forth in claim 3 , wherein the implant is formed from a material with a modulus of elasticity of between 40 and 50 GPa.

5. An implant as set forth in claim 1 , wherein the biodegradable material is a biodegradable magnesium, iron or tungsten alloy.

6. An implant as set forth in claim 5 , wherein the magnesium alloy is an alloy of type WE.

7. An implant as set forth in claim 6 , wherein the alloy is of type WE43.

8. An implant as set forth in claim 7 , wherein the implant of a biodegradable alloy is of such a nature that a desired radial strength only occurs at between 1 and 120 h after introduction into 37° C. artificial plasma in accordance with EN ISO 10993-15:2000.

9. An implant as set forth in claim 8 , wherein a desired radial strength occurs between 24 and 72 h after introduction into 37° C. artificial plasma in accordance with EN ISO 10993-15:2000.

10. An implant as set forth in claim 2 , wherein the biodegradable material is a biodegradable magnesium, iron or tungsten alloy.

11. An implant as set forth in claim 3 wherein the biodegradable material is a biodegradable magnesium, iron or tungsten alloy.

12. An implant as set forth in claim 4 , wherein the biodegradable material is a biodegradable magnesium, iron or tungsten alloy.

13. An implant as set forth in claim 10 , wherein the magnesium alloy is an alloy of type WE.

14. An implant as set forth in claim 11 , wherein the magnesium alloy is an alloy of type WE.

15. An implant as set forth in claim 12 , wherein the magnesium alloy is an alloy of type WE.

16. An implant as set forth in claim 13 , wherein the alloy is of type WE43.

17. An implant as set forth in claim 14 , wherein the alloy is of type WE43.

18. An implant as set forth in claim 16 , wherein the implant of a biodegradable alloy is of such a nature that a desired radial strength only occurs at between 1 and 120 h after introduction into 37° C. artificial plasma in accordance with EN ISO 10993-15:2000.

19. An implant as set forth in claim 15 , wherein the implant of a biodegradable alloy is of such a nature that a desired radial strength only occurs at between 1 and 120 h after introduction into 37° C. artificial plasma in accordance with EN ISO 10993-15:2000.

20. A method of treating a patient, the method comprising inserting an endovascular implant into the patient, wherein the implant comprises a biodegradable material having a tubular main body which is open at the ends, wherein the implant is adapted to be dilatable from an unexpanded condition to an expanded condition, and wherein, the implant is adapted such that, prior to implantation, when the implant in the expanded condition is subjected to a radially acting compression pressure between about 5 and about 30 kPa (about 0.05-0.3 bar), the cross-sectional area of the implant is reduced to 70 percent or less of the original cross-sectional area or an internal volume of the implant is reduced to 70 percent or less of the original internal volume.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 25, 2018
From: BIOTRONIK VI PATENT AG
To: BIOTRONIK AG
Reel/Frame 047166/0462 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 9, 2006
From: GEROLD, BODO; HARDER, CLAUS; HEUBLEIN, EVA, LEGAL REPRESENTATIVE OF THE ESTATE OF BERND HEUBLEIN (DECEASE); HEUBLEIN, CHRISTOPH, LEGAL REPRESENTATIVE OF THE ESTATE OF BERND HEUBLEIN (DECEASE); MUELLER, HEINZ; HEUBLEIN, NORA, LEGAL REPRESENTATIVE OF THE ESTATE OF BERND HEUBLEIN (DECEASE)
To: BIOTRONIK VI PATENT AG
Reel/Frame 017607/0557 →
Priority Claims (1)
DE 10 2004 044 679 · Sep 9, 2004 · national
Continuity (1)
Related Publication 20060064160A1 · Mar 23, 2006