Methods for modulating phototoxicity
View Patent ↗The invention relates to methods for modulating photodamage via the use of collagen derived molecules which either enhance or inhibit damage caused by ultraviolet light.
1. A method for enhancing photodamage in a subject in need thereof, comprising applying to skin of said subject an amount of a photodamage modulator sufficient to enhance photodamage caused by ultraviolet light wherein said modulator is selected from the group consisting of a modulator which has a structure consisting of an N-alkyl-3-hydroxypyridine or salt thereof, wherein the alkyl moiety is 2-20 carbon atoms, vitamin B6, pyridinoline, and 3-hydroxypyridine.
2. The method of claim 1 , wherein said modulator is collagen derived.
3. The method of claim 1 , wherein said modulator is N-alkyl-3-hydroxypyridine or salt thereof.
4. The method of claim 1 , wherein said alkyl moiety is an ethyl group.
5. The method of claim 1 , wherein said modulator is connected to a carrier molecule.
6. The method of claim l, wherein said modulator is vitamin B6, pyridinoline, or 3-hydroxypyridine.
7. The method of claim 1 , comprising applying said modulator in the form of a cream, lotion, shampoo, spray or patch.