Dosage forms having a microreliefed surface and methods and apparatus for their production
View Patent ↗The present invention provides an edible dosage form that incorporates optical elements (e.g., printed patterns, microrelief gratings, and/or macrorelief gratings), capable of producing unique optical effects and images in order to enable a user to better identify and differentiate the dosage forms, as well as to improve the detection of counterfeit production thereof, wherein the edible dosage forms may be made in a variety of ways to incorporate the optical elements therein.
1. A dosage form comprised of:
a) a core, wherein the core comprises a pharmaceutically active agent; and
b) an outer layer comprised of a carrier and the composition comprised of polymeric film flakes having at least one surface wherein the polymeric film flakes possess a microrelief on the at least one surface and wherein the microrelief is a high resolution diffraction grating or dovid.
2. The dosage form of claim 1 , wherein the outer layer is further comprised of a polymeric matrix containing at least one polymer in a substantially amorphous form.
3. The dosage form of claim 1 , wherein the core further comprises a pharmaceutically active agent.
4. The dosage form of claim 1 , wherein the microrelief is a high resolution diffraction grating.
5. The dosage form of claim 1 , wherein the microrelief is a dovid.
6. The dosage form of claim 2 , wherein the core further comprises a pharmaceutically active agent.
7. The dosage form of claim 2 , wherein the microrelief is a high resolution diffraction grating.
8. The dosage form of claim 3 , wherein the microrelief is a high resolution diffraction grating.
9. The dosage form of claim 6 , wherein the microrelief is a high resolution diffraction grating.
10. The dosage form of claim 2 , wherein the microrelief is a dovid.
11. The dosage form of claim 3 , wherein the microrelief is a dovid.
12. The dosage form of claim 6 , wherein the microrelief is a dovid.
13. The dosage form of claim 5 , wherein the dovid is a hologram.
14. The dosage form of claim 10 , wherein the dovid is a hologram.
15. The dosage form of claim 11 , wherein the dovid is a hologram.
16. The dosage form of claim 12 , wherein the dovid is a hologram.
17. The dosage form of claim 13 , wherein the dovid is a hologram.