Dural graft and method of preparing the same
A dural graft is provided having improved stiffness characteristics relative to conventional dural substitutes. The dural graft can be formed from a collagen material having a stiffness between about 0.1 pounds per inch (lb./in.) and 0.25 lb./in. Relative to the collagen material forming conventional dural graft substitutes, the decreased stiffness of the collagen material of the present dural graft can provide the graft with a relatively improved or increased pliability. As a result of the increased pliability, the dural graft can sufficiently conform to a curvature of a tissue surface to which it is applied, such as the curved surface of a meningeal membrane. The reduced stiffness of the collagen material can also provide for a relatively improved or increased flexibility or elasticity of the dural graft. The increased flexibility of the dural graft minimizes tearing of the graft when handled or manipulated during an implantation procedure.
1. A method for manufacturing a dural graft substitute, comprising:
delivering energy to a collagen material at a power level and for a period of time sufficient to reduce a stiffness of the collagen material to a stiffness in a range of about 0.01 pounds per inch to 0.25 pounds per inch.
2. The method of claim 1 , comprising reducing the stiffness of the collagen material to a stiffness in a range of about 0.04 pounds per inch to 0.12 pounds per inch.
3. The method of claim 1 , wherein the energy is microwave energy.
4. The method of claim 3 , wherein delivering microwave energy comprises delivering microwave energy to the collagen material at a power of in a range of about 50 Watts to 1200 Watts for a duration in the range of about of about 5 second to 180 seconds.
5. The method of claim 3 , wherein delivering microwave energy comprises delivering microwave energy to the collagen material at a power of in a range of about 200 Watts to 800 Watts for a duration in the range of about of about 15 second to 60 seconds.