Medical device
A medical device for example a wound dressing having antibacterial and optionally, antifungal properties, are provided together with methods for making the device. An exemplary dressing includes a layer of silver-containing fabric, (optionally) a layer of absorbent material, and (optionally) a layer of flexible air-permeable and/or water-impermeable material. The dressing can be used for prophylactic and therapeutic care and treatment of skin infections and surface wounds (including surgical incisions), as a packing material, and as a swab for surface cleaning.
1. A device comprising:
a first conformable, conductive fabric comprising
a) fibers or foams coated with an anti-microbial metal, wherein the coated fibers or foams provide a surface resistance of about 10 ohms/cm 2 to about 0.001 ohms/cm 2 to the conductive fabric, wherein the fibers comprise multiple filaments; and
b) a plurality of apertures effective to provide the device with a liquid wicking value in a range of about 5% to 95% to allow removal of fluid from the wound through the device, wherein the apertures are positioned to facilitate uniform application of the device to a wound when the device is under negative pressure.
2. The device of claim 1 , wherein the apertures have a size range that allows liquids and gases to pass through.
3. The device of claim 1 , wherein the anti-microbial metal comprises silver.
4. The device of claim 1 , wherein the anti-microbial metal comprises approximately 5 to about 40 wt. % silver.
5. The device of claim 1 , wherein the surface resistance is no greater than approximately 5 Ω/cm 2 .
6. The device of claim 1 , wherein the surface resistance is no greater than approximately 1 Ω/cm 2 .
7. The device of claim 1 , wherein the fabric comprises one or more polymers, fibers, yarns, foams, or combinations thereof.
8. The device of claim 7 , wherein the one or more yarns comprises a synthetic polymer fiber and an elastic component.
9. The device of claim 8 , wherein the elastic component comprises a long-chain synthetic polymer comprising at least 85% of a segmented polyurethane.
10. The device of claim 9 , wherein the elastic component is not coated with the anti-microbial metal.
11. The device of claim 9 , wherein the elastic component is wrapped around the synthetic polymer fiber.
12. The device of claim 11 , wherein the synthetic polymer fiber comprises nylon.
13. The device of claim 1 , further comprising a second layer.
14. The device of claim 13 , wherein the second layer comprises a second layer of conformable, conductive fabric.
15. The device of claim 14 , wherein the second layer of conformable conductive fabric is separated from the first conformable, conductive fabric by a plurality of supports.
16. The device of claim 15 , wherein the supports comprise nylon.
17. The device of claim 15 , wherein the supports are not coated with an anti-microbial metal.
18. The device of claim 17 , wherein the nylon supports are uniformly coated with silver.
19. The device of claim 18 , wherein the fabric comprises woven or knitted fibers or yarns.
20. The device of claim 17 , wherein the fabric comprises non-woven fibers or yarns.
21. The device of claim 14 , further comprising a third layer adjacent to said second layer, said third layer made of an air-permeable material.
22. The device of claim 14 , further comprising a third layer adjacent to said second layer, said third layer made of a water-permeable material.
23. The device of claim 1 , wherein the device maintains a transepithelial electrical potential of a wound at about −10 mvolts to about −70 mvolts.