IP Library Granted Patent US 7,288,520
Granted Patent B2
US 7,288,520 · App. 11/255,821 · Granted Oct 30, 2007

Cyclosporin compositions

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Quick Facts
Patent No.
US 7,288,520
App. No.
11/255,821
Granted
Oct 30, 2007
Kind
B2
Abstract

A composition is disclosed herein comprising from about 0.001% to about 0.4% cyclosporin A, castor oil, and a surfactant selected from the group consisting of alcohol ethoxylates, alcohols, alkyl glycosides, alkyl polyglycosides, alkylphenol ethoxylates, amine oxides, block polymers, carboxylated alcohol or alkylphenol ethoxylates, carboxylic acids/fatty acids, cellulose derivatives, ethoxylated alcohols, ethoxylated alkylphenols, ethoxylated aryl phenols, ethoxylated fatty acids, ethoxylated fatty acids, ethoxylated fatty esters and oils, fatty alcohols, fatty esters, glycol esters, lanolin-based derivatives, lecithin and lecithin derivatives, lignin and lignin derivatives, methyl esters, monoglycerides and derivatives, phosphalipids, polyacrylic acids, polyethylene glycols, polyethylene oxide-polypropylene oxide copolymers, polyethylene oxides, polymeric surfactants, polypropylene oxides, propoxylated alcohols, propoxylated alkyl phenols, propoxylated fatty acids, protein-based surfactants, sarcosine derivatives, silicone-based surfactants, sorbitan derivatives, stearates, sucrose and glucose esters and derivatives, and combinations thereof.

Claims (3)

1. A composition comprising from about 0.001% to about 0.4% cyclosporin A, castor oil, and Polyoxyethylene 20 (POE (20)) sorbitan monolaurate wherein said composition is an ophthalmically acceptable emulsion.

2. The composition of claim 1 comprising from about 0.005% to about 0.05% cyclosporin A.

3. The composition of claim 2 comprising about 0.05% cyclosporin A.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2017
From: ALLERGAN, INC.
To: SAINT REGIS MOHAWK TRIBE
Reel/Frame 043830/0446 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 4, 2005
From: CHANG, JAMES N.; OLEJNIK, OREST; FIRESTONE, BRUCE A.
To: ALLERGAN, INC.
Reel/Frame 016979/0723 →