IP Library › Granted Patent US 7,485,650
Granted Patent B2
US 7,485,650 · App. 11/259,765 · Granted Feb 3, 2009

High affinity ligands for nociceptin receptor ORL-1

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Quick Facts
Patent No.
US 7,485,650
App. No.
11/259,765
Granted
Feb 3, 2009
Kind
B2
Abstract

The compound of the formula or a pharmaceutically acceptable salt or solvate thereof, pharmaceutical compositions therefore, and the use of said compounds as nociceptin receptor inhibitors useful in the treatment of anxiety are disclosed.

Claims (5)

1. A compound represented by the formula

or a pharmaceutically acceptable salt or solvate thereof.

2. A pharmaceutical composition comprising a therapeutically effective amount of compound of claim 1 in combination with a pharmaceutically acceptable carrier.

3. A method of treating anxiety comprising administering an effective amount of a compound of claim 1 to a mammal or a non-mammalian species in need of such treatment.

4. The method of claim 3 wherein the mammals treated are selected from the group consisting of humans, domestic animals, livestock and wild animals, and the non-mammalian species are selected from aquatic and avian species.