IP Library Granted Patent US 8,694,118
Granted Patent B2
US 8,694,118 · App. 11/262,465 · Granted Apr 8, 2014

Variable output ramping for an implantable medical device

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Quick Facts
Patent No.
US 8,694,118
App. No.
11/262,465
Granted
Apr 8, 2014
Kind
B2
Abstract

A method, system, and apparatus for providing a stimulation signal comprising a variable ramping portion using an implantable medical device (IMD). The first electrical comprises a first ramping portion. The first ramping portion comprises a first parameter selected from the group consisting of an amplitude, a rate of change of the amplitude, a time period of a rate of change of the amplitude, a pulse width, a rate of change of the pulse width, a time period of a rate of change of the pulse width, a frequency, a rate of change of the frequency, a time period of a rate of change of the frequency, and a duration of a time period of the ramping portion, the first parameter having a first value. The first electrical signal is applied to a target location of the patient's body. A second electrical signal comprising a second ramping portion is generated. The second ramping portion comprises the first parameter having a second value that is different from the first value. The second electrical signal is applied to a target location of the patient's body.

Claims (18)

1. An implantable medical device for providing an electrical neurostimulation therapy to a patient, the implantable medical device comprising:

a ramping signal controller configured to generate via a ramping signal generator a first electrical signal comprising a first ramping portion which is based on a first parameter including at least one of an amplitude, a rate of change of the amplitude, a time period of the rate of change of the amplitude, a pulse width, a rate of change of the pulse width, a time period of a rate of change of the pulse width, a frequency, a rate of change of the frequency, a time period of a rate of change of the frequency, and a duration of a time period of the first ramping portion, the first parameter having a first value;

the first electrical signal being applied to a target location of the patient's body;

the ramping signal controller being configured to determine via an efficacy feedback unit a second value for the first parameter for a second electrical signal based on a neural conditioning value, the second value being different than the first value and the second value having a randomized portion;

the ramping signal controller being further configured to generate via the ramping signal generator the second electrical signal comprising a second ramping portion based on the second value, wherein the second value is chosen by the ramping signal controller to reduce neural conditioning; and

wherein the second electrical signal is applied to the target location of the patient's body.

2. The implantable medical device of claim 1 , wherein the first electrical signal comprising the first ramping portion includes at least one of a ramping-up portion having the first parameter and a ramping-down having the first parameter.

3. The implantable medical device of claim 2 , wherein the ramping portion comprises at least one of the ramping-up portion having the second value and the ramping-down portion having the second value.

4. The implantable medical device of claim 1 , wherein the second electrical signal is based on the second value that differs randomly from the first value.

5. The implantable medical device of claim 1 , wherein the second electrical signal is utilized to provide a multi-phasic signal for the ramping portion.

6. The implantable medical device of claim 1 , wherein the second electrical signal is based on at least one of an external command, an internal programmed command, and a feedback indication.

7. The implantable medical device of claim 1 , wherein the second electrical signal is based on data relating to an efficacy associated with the stimulation.

8. A method for providing an electrical neurostimulation therapy to a patient using an implantable medical device (IMD), comprising:

generating a first electrical signal comprising a first ramping portion which is based on a first parameter including at least one of an amplitude, a time period of a rate of change of the amplitude, a pulse width, a rate of change of the pulse width, a time period of the rate of change of the pulse width, a frequency, a rate of change of the frequency, a time period of a rate of change of the frequency, and a duration of a time period of the first ramping portion, the first parameter having a first value;

applying the first electrical signal to a target location of the patient's body;

determining a second value for the first parameter for a second electrical signal based on a neural conditioning value, the second value being different than the first value and the second value having a randomized portion;

generating the second electrical signal comprising a second ramping portion based on the second value, wherein the second value differs randomly from the first value and is chosen by the IMD to reduce neural conditioning; and

applying the second electrical signal to the target location of the patient's body.

Assignments (7)
RELEASE OF SECURITY INTEREST Recorded Sep 20, 2021
From: ACF FINCO I LP
To: LIVANOVA USA, INC.
Reel/Frame 057552/0378 →
SECURITY INTEREST Recorded Aug 16, 2021
From: LIVANOVA USA, INC.
To: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
Reel/Frame 057188/0001 →
RELEASE OF SECURITY INTEREST Recorded Aug 16, 2021
From: ARES CAPITAL CORPORATION, AS AGENT FOR THE LENDERS
To: LIVANOVA USA, INC.
Reel/Frame 057189/0001 →
PATENT SECURITY AGREEMENT Recorded Dec 30, 2020
From: LIVANOVA USA, INC.
To: ACF FINCO I LP, AS COLLATERAL AGENT
Reel/Frame 054881/0784 →
CHANGE OF NAME Recorded Jun 29, 2020
From: CYBERONICS, INC.
To: LIVANOVA USA, INC.
Reel/Frame 053306/0229 →
PATENT SECURITY AGREEMENT Recorded Jun 17, 2020
From: LIVANOVA USA, INC.
To: ARES CAPITAL CORPORATION, AS COLLATERAL AGENT
Reel/Frame 053673/0675 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 28, 2005
From: ARMSTRONG, RANDOLPH K.
To: CYBERONICS, INC.
Reel/Frame 017158/0801 →