β

1. A compound of the formula:

wherein:

m is 2;

n is 0 or 1;

A 1 , A 2 and A 3 are carbon;

Het is at the ortho-position relative to X and is isoxazol-3-yl;

R 1 , R 2 and R 3 are H;

R 4 and R 5 are independently H or methyl at each occurrence;

the 6,5 ring system is connected to the (CR 4 R 5 ) 2 moiety at the 2 or 3-position of the 6,5 ring system;

R 6 is independently at each occurrence hydroxyl or methyl;

R 7 is at the 6- or 7-position of the 6,5 ring system to which it is attached and is selected from H, O(CH 2 ) p R 12 or thienyl;

X is OCH 2 ;

p is 0 or 1; and

R 12 is CO 2 R 15 , CONH 2 , phenyl optionally substituted with one or two —CF 3 groups or pyridyl substituted once with CONH 2 where R 15 is H or C 1 -C 6 alkyl; or a pharmaceutical salt thereof.

2. A compound which is:

or a pharmaceutical salt thereof.

3. The compound of claim 1 which is the hydrochloride salt.

4. A pharmaceutical formulation comprising a compound of claim 1 and a pharmaceutical carrier.

5. A method of treating Type 2 Diabetes comprising administering to a patient in need thereof an effective amount of a compound of claim 1 .

6. A method of treating obesity comprising administering to a patient in need thereof an effective amount of a compound of claim 1 .