Cholesterol measurement system and method
A cholesterol testing system and method are provided in which cholesterol values determined from testing a sample are analyzed and normalized to generate a set of cholesterol values.
1 . A system for determining a set of physiological parameter basis class values, comprising:
a unit that generates a profile based on a physiological parameter sample; and
a computer system that analyzes the profile and generates a set of physiological parameter class values based on the profile, the computer system having means for dynamically initializing a set of parameters to generate a set of initial parameters and means for determining a set of physiological parameter values based on the set of parameters and the profile.
2 . The system of claim 1 , wherein the physiological parameter further comprise one of cholesterol, lipoproteins, protein concentration, glucose concentration and cellular type.
3 . The system of claim 2 , wherein the determining means further comprising means for fitting a set of predetermined subcurves to the profile wherein each physiological parameter class has a subcurve.
4 . The system of claim 3 , wherein the fitting means further comprising means for using a Levenberg Marquardt optimization.
5 . The system of claim 4 , wherein the optimization means further comprises means for comparing a calculated curve point to a fitted curve point to generate an error function, means for adjusting the fitting function based on the error function.
6 . The system of claim 3 , wherein the fitting means further comprising means for determining a particular subcurve for a particular physiological parameter class based on a Weibull equation.
7 . The system of claim 4 , wherein the fitting means further comprising means for determining a particular subcurve for a particular physiological parameter class based on a Weibull equation.
8 . The system of claim 1 , wherein the determining means further comprising means for performing a direct area measurement of an area under the profile in order to determine each physiological parameter class value.
9 . The system of claim 2 , wherein the unit further comprises a spectrometer that generates an absorption profile based on the physiological parameter sample.
10 . A system for determining a set of cholesterol class values, comprising:
a detector that generates a value corresponding to a cholesterol sample; and
a computer system that analyzes the cholesterol sample value and generates a set of cholesterol class values based on the cholesterol sample value, the computer system having means for dynamically initializing a set of parameters to generate a set of initial parameters and means for determining a set of cholesterol values based on the set of parameters and the cholesterol sample value.
11 . The system of claim 10 , wherein the determining means further comprising means for fitting a set of predetermined subcurves to the cholesterol sample value wherein each cholesterol class has a subcurve.
12 . The system of claim 11 , wherein the fitting means further comprising means for using a Levenberg Marquardt optimization.
13 . The system of claim 12 , wherein the optimization means further comprises means for comparing a calculated curve point to a fitted curve point to generate an error function, means for adjusting the fitting function based on the error function.
14 . The system of claim 11 , wherein the fitting means further comprising means for determining a particular subcurve for a particular cholesterol class based on a Weibull equation.
15 . The system of claim 12 , wherein the fitting means further comprising means for determining a particular subcurve for a particular cholesterol class based on a Weibull equation.
16 . A computer implemented method for determining a set of physiological parameter class values, comprising:
determining a value corresponding to a physiological parameter sample;
analyzing the physiological parameter sample value to generate a set of physiological parameter class values based on the physiological parameter sample value; and
wherein the analyzing further comprises dynamically initializing a set of parameters to generate a set of initial parameters and determining a set of physiological parameter values based on the set of parameters and the physiological parameter sample value.
17 . The method of claim 16 , wherein the physiological parameter further comprise one of cholesterol, lipoproteins, protein concentration, glucose concentration and cellular type..
18 . The method of claim 17 , wherein determining the set of physiological parameter values further comprises fitting a set of predetermined subcurves to the profile wherein each physiological parameter class has a subcurve.
19 . The method of claim 18 , wherein the fitting further comprising using a Levenberg Marquardt optimization.
20 . The method of claim 19 , wherein the fitting further comprises comparing a calculated curve point to a fitted curve point to generate an error function and adjusting the fitting function based on the error function.
21 . The method of claim 18 , wherein the fitting further comprising determining a particular subcurve for a particular physiological parameter class based on a Weibull equation.
22 . The method of claim 19 , wherein the fitting further comprising determining a particular subcurve for a particular physiological parameter class based on a Weibull equation.
23 . The method of claim 17 , wherein the determining the set of physiological parameter values further comprises performing a direct area measurement of an area under the profile in order to determine each physiological parameter class value.
24 . A computer implemented method for determining a set of cholesterol class values, comprising:
determining a value corresponding to a cholesterol sample;
analyzing the cholesterol sample value to generate a set of cholesterol class values based on the cholesterol sample value; and
wherein the analyzing further comprises dynamically initializing a set of parameters to generate a set of initial parameters and determining a set of cholesterol values based on the set of parameters and the cholesterol sample value.
25 . The method of claim 24 , wherein the determining further comprises fitting a set of predetermined subcurves to the cholesterol sample value wherein each cholesterol class has a subcurve.
26 . The method of claim 25 , wherein the fitting further comprising using a Levenberg Marquardt optimization.
27 . The method of claim 26 , wherein the optimization further comprises comparing a calculated curve point to a fitted curve point to generate an error function and adjusting an error function based on the error function.
28 . The method of claim 25 , wherein the fitting further comprising determining a particular subcurve for a particular cholesterol class based on a Weibull equation.
29 . The method of claim 26 , wherein the fitting further comprising determining a particular subcurve for a particular cholesterol class based on a Weibull equation.
30 . A system for determining a set of cholesterol basis class values, comprising:
a detector that generates an absorption profile based on a cholesterol sample; and
a computer system that analyzes the absorption profile and generates a set of cholesterol class values based on the absorption profile, the computer system having means for dynamically initializing a set of parameters to generate a set of initial parameters and means for determining a set of cholesterol values based on the set of parameters and the absorption profile.
31 . The system of claim 30 , wherein the determining means further comprising means for fitting a set of predetermined subcurves to the absorption profile wherein each cholesterol class has a subcurve.
32 . The system of claim 31 , wherein the fitting means further comprising means for using a Levenberg Marquardt optimization.
33 . The system of claim 32 , wherein the optimization means further comprises means for comparing a calculated curve point to a fitted curve point to generate an error function, means for adjusting the fitting function based on the error function.
34 . The system of claim 31 , wherein the fitting means further comprising means for determining a particular subcurve for a particular cholesterol class based on a Weibull equation.
35 . The system of claim 32 , wherein the fitting means further comprising means for determining a particular subcurve for a particular cholesterol class based on a Weibull equation.
36 . The system of claim 30 , wherein the determining means further comprising means for performing a direct area measurement of an area under the absorption profile in order to determine each cholesterol class value.
37 . The system of claim 30 , wherein the detector further comprises a spectrometer.