Compositions and processes for accelerated wound healing using novel fibrous webbings

1. A wound healing multilayer bandage comprising:

(i) a webbing for placement in direct contact with a wound having a periphery; and

(ii) a first membrane comprising at least one water-insoluble polymer;

wherein the webbing has a biologically degradable or a biologically resorbable fiber structure;

wherein the webbing is a spun-bonded webbing;

wherein the webbing comprises at least one partially or completely hydrolytically condensed silicon compound;

wherein the first membrane is water-impervious or semi-permeable;

wherein the first membrane either (a) further comprises an adhesive portion wherein the adhesive portion adheres to skin tissue at the wound periphery or (b) does not comprise an adhesive portion and bonds with an adhesive which is applied to the skin tissue at the wound periphery, wherein the first membrane is configured to seal the wound off from a surrounding environment when the first membrane is adhered to the skin tissue at the wound periphery or bonded to an adhesive which is applied to the skin tissue at the wound periphery; and

wherein either no bond or a loose, frangible adhesive bond exists between the first membrane and the webbing.

2. The multilayer bandage according to claim 1 , wherein the water-insoluble polymer is selected from the group consisting of polypropylene, polyvinylchloride and polyurethane.

3. The multilayer bandage according to claim 1 , wherein the first membrane is a self-adhesive hydropolymer.

4. The multilayer bandage according to claim 1 , wherein the webbing is a fibrous webbing.

5. The multilayer bandage according to claim 1 , wherein the silicon compound comprises a monomer of the formula SiX 4 wherein residues X 1 , X 2 , X 3 , and X 4 are independently selected from the group consisting of hydroxyl, hydrogen, halogen, amino, alkoxy, alkyloxy, alkylcarbonyl and alkoxycarbonyl.

6. The multilayer bandage according to claim 1 , wherein the silicon compound comprises a monomer of the formula SiX 4 wherein residues X 1 , X 2 , X 3 , and X 4 are derived from an alkyl and can be interrupted by an oxygen atom, a sulfur atom or an amino group and wherein residues X 1 , X 2 , X 3 , and X 4 are identical or different.

7. The multilayer bandage according to claim 6 , wherein residues X 1 , X 2 , X 3 , and X 4 are ethyl.

8. The multilayer bandage according to claim 7 , wherein the webbing comprises a morphogenic factor selected from the group consisting of a steroid, a cytokine, an interleukin, a bone morphogenetic protein, an antibody, TNF-α, TGF-(β½, IGF, PDGF, and EGF.

9. The multilayer bandage according to claim 1 , wherein the webbing comprises an organic compound selected from the group consisting of a nucleotide, an amino acid and polymers thereof.

10. A wound healing multilayer bandage comprising:

(i) a webbing for placement in direct contact with a wound having a periphery; and

(ii) a first membrane comprising at least one water-insoluble polymer;

wherein the webbing has a biologically degradable or a biologically resorbable fiber structure;

wherein the webbing is a spun-bonded webbing;

wherein the webbing comprises at least one partially or completely hydrolytically condensed silicon compound;

wherein the first membrane is water-impervious;

wherein the first membrane either (a) further comprises an adhesive portion wherein the adhesive portion adheres to skin tissue at the wound periphery or (b) does not comprise an adhesive portion and bonds with an adhesive which is applied to the skin tissue at the wound periphery, wherein the first membrane is configured to seal the wound off from a surrounding environment when the first membrane is adhered to the skin tissue at the wound periphery or bonded to an adhesive which is applied to the skin tissue at the wound periphery; and

wherein either no bond or a loose, frangible adhesive bond exists between the first membrane and the webbing; and

(iii) a second membrane comprising at least one water-soluble polymer;

wherein the second membrane is disposed between the first membrane and the webbing.

11. The multilayer bandage according to claim 10 , wherein the water-soluble polymer is carboxymethylcellulose.

12. The multilayer bandage according to claim 10 , wherein a bond exists between the second membrane and the webbing and wherein the bond is a loose, frangible adhesive bond.

13. The multilayer bandage according to claim 10 , wherein no adhesive bond exists between the second membrane and the webbing.

14. The multilayer bandage according to claim 10 , wherein a bond exists between the first membrane and the second membrane and wherein the bond is a loose, frangible adhesive bond or a stable, non-frangible adhesive bond.

15. A wound healing multilayer bandage comprising:

(i) a webbing for placement in direct contact with a wound having a periphery; and

(ii) a first membrane comprising at least one water-insoluble polymer;

wherein the webbing has a biologically degradable or a biologically resorbable fiber structure;

wherein the webbing is a spun-bonded webbing;

wherein the webbing comprises at least one partially or completely hydrolytically condensed silicon compound;

wherein the first membrane is water-impervious;

wherein the first membrane either (a) further comprises an adhesive portion wherein the adhesive portion adheres to skin tissue at the wound periphery or (b) does not comprise an adhesive portion and bonds with an adhesive which is applied to the skin tissue at the wound periphery, wherein the first membrane is configured to seal the wound off from a surrounding environment when the first membrane is adhered to the skin tissue at the wound periphery or bonded to an adhesive which is applied to the skin tissue at the wound periphery; and

wherein either no bond or a loose, frangible adhesive bond exists between the first membrane and the webbing; and

(iii) a dressing selected from the group consisting of an alginate, a collagen sponge, a polyurethane foam, a polyurethane foam pad, a hydrocolloid, a hydrogel and a hydropolymer, and wherein the dressing is disposed between the webbing and the first membrane.

16. The multilayer bandage according to claim 15 , wherein a bond exists between the dressing and the webbing and wherein the bond is a loose, frangible adhesive bond.

17. The multilayer bandage according to claim 15 , wherein no adhesive bond exists between the dressing and the webbing.

18. The multilayer bandage according to claim 15 , wherein a bond exists between the dressing and the first membrane and wherein the bond is either a loose, frangible adhesive bond or a stable, non-frangible adhesive bond.

19. A method for treating a wound having a periphery, the method comprising:

placing a webbing in direct contact with a wound, wherein the webbing is spun-bonded webbing and has a biologically degradable or a biologically resorbable fiber structure, wherein the webbing comprises at least one partially or completely hydrolytically condensed silicon compound; and

applying a first membrane onto a top side of the webbing, wherein the top side of the webbing is located opposite to the wound, wherein the first membrane is water-impervious or semi-permeable such that moisture is prevented from evaporating outwardly from the wound through the first membrane, wherein the first membrane comprises at least one water-insoluble polymer, wherein the first membrane either (a) further comprises an adhesive portion wherein the adhesive portion adheres to skin tissue at the periphery of the wound or (b) does not comprise an adhesive portion and bonds with an adhesive which is applied to the skin tissue at the periphery of the wound, and further wherein either no bond or a loose, frangible adhesive bond exists between the first membrane and the webbing.