Endoluminal stent, self-supporting endoluminal graft and methods of making same
View Patent ↗An endoluminal stent composed of a plurality of first structural elements arrayed to form the circumference of the stent and extending along the longitudinal axis of the stent, and a plurality of second structural elements that interconnect adjacent pairs of first structural elements. The plurality of first structural elements have either a linear shape or a generally sinusoidal configuration with either a regular or irregular periodicity or regions of regular and regions of irregular periodicity between the peaks and troughs of the pattern, with the peaks and troughs projecting from the first structural elements in the circumferential axis. The plurality of second structural elements are generally linear or sinusoidal-shaped members which interconnect an apex of a peak of one of the plurality of first structural elements with an apex of a valley of a second and adjacent one of the plurality of first structural elements. Each of the plurality of second structural elements are generally oriented parallel to the circumferential axis of the stent.
1. An intraluminal device comprising a generally tubular member having a plurality of struts and a plurality of interconnecting members, forming circumferential walls thereof, each of the plurality of struts further having a generally sinusoidal curve thereto defining peaks and valleys of each of the plurality of struts and arranged generally sinusoidal and parallel to a longitudinal axis of the generally tubular member, each of the plurality of struts being in spaced-apart, in-phase relationship with respect to an adjacent one of the plurality of struts substantially about a circumferential aspect of the tubular member and the plurality of interconnecting members interconnecting adjacent pairs of struts and extending between a peak of a first strut and a valley of a second strut, wherein no more than one interconnecting member connects to any given peak or valley.
2. The device according to claim 1 , wherein each of the struts are integral and monolithic with each of the plurality of interconnecting members.
3. The device according to claim 1 , wherein the plurality of struts is discrete from and conjoined to the plurality of interconnecting members.
4. The device according to claim 1 , wherein the struts and the interconnecting members are made of the same material.
5. The device according to claim 1 , wherein the struts and the interconnecting members are made of different biocompatible materials.
6. The device according to claim 5 , wherein the struts have material properties different and distinct from the interconnecting members.
7. The device according to claim 1 , wherein the struts and the interconnecting members further comprise luminal surfaces thereof having controlled heterogeneities thereupon.
8. The device according to claim 7 , wherein the controlled heterogeneities are selected from the group consisting of grain size, grain phase, grain material composition, stent material composition and surface topography.
9. The device according to claim 7 , wherein the controlled heterogeneities define polar and non-polar binding sites for binding blood plasma proteins.
10. The device according to claim 7 , wherein the controlled heterogeneities are dimensioned to have a blood contact surface area substantially similar in size as endothelial cell surface integrin clusters.
11. The device according to claim 1 , wherein the struts and the interconnecting members are made of materials selected from the group consisting of titanium, vanadium, aluminum, nickel, tantalum, zirconium, chromium, silver, gold, silicon, magnesium, niobium, scandium, platinum, cobalt, palladium, manganese, molybdenum and alloys thereof, and stainless steel.
12. An intraluminal stent comprising a generally tubular member having a plurality of generally sinusoidal members being substantially parallel to a longitudinal axis of the generally tubular member and extending along the entire length of the longitudinal axis, each of the plurality of generally sinusoidal members being in spaced-apart, in-phase relationship with respect to an adjacent one of the plurality of generally sinusoidal members substantially about a circumferential aspect of the tubular member; and a plurality of interconnecting members interconnecting adjacent pairs of the generally sinusoidal members and extending between a peak of a first generally sinusoidal member and a valley of a second, circumferentially adjacent generally sinusoidal member, such that no more than one interconnecting member connects to any given peak or valley of adjacent generally sinusoidal members.