IP Library Granted Patent US 7,445,640
Granted Patent B2
US 7,445,640 · App. 11/329,273 · Granted Nov 4, 2008

Implant with composite coating

Assignee: Hayes Medical, Inc.
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Quick Facts
Patent No.
US 7,445,640
App. No.
11/329,273
Granted
Nov 4, 2008
Kind
B2
Abstract

Systems and methods are described for implants with composite coatings to promote tissue in-growth and/or on-growth. An implant includes: a substrate; a structured surface formed on at least a portion of the substrate; and a biocompatible coating deposited on at least a fraction of the structured surface. The systems and methods provide advantages in that the implant has good biocompatibility while the biocompatible coating has good strength.

Claims (48)

1. An osteoconductive process comprising:

providing an implant comprising:

a substrate;

a structured surface formed on at least a portion of the substrate, the structured surface being of the same material as the substrate; and

a biocompatible coating deposited by a selected one of (i) arc evaporation physical vapor deposition and (ii) chemical vapor deposition on at least a fraction of the structured surface, the coating being softer and more biocompatible than the substrate and the structured surface;

testing for the presence of high adhesion between the coating and the structured surface; and

contacting a bone under in vivo conditions with the implant.

2. An osteoconductive process-comprising:

providing a composition for an implant, the composition comprising a biocompatible material coated by a selected one of (i) arc evaporation physical vapor deposition and (ii) chemical vapor deposition on a structured surface defined by a substrate, the coating being softer and more biocompatible than the substrate and the structured surface;

testing for the presence of high adhesion between the coating and the structured surface, and

contacting a bone under in vivo conditions with the composition.

3. A method for orthopedic surgery which comprises:

providing an implant comprising:

a substrate;

a structured surface formed on a portion of the substrate, the structured surface being of the same material as the substrate; and

a biocompatible coating deposited by a selected one of (i) arc evaporation physical vapor deposition and (ii) chemical vapor deposition on at least a fraction of the structured surface, the coating being softer and more biocompatible than the substrate and the structured surface;

testing for the presence of high adhesion between the coating and the structured surface; and

contacting a bone under in vivo conditions with the implant;

wherein the portion of the substrate is fixed with at least one of tissue in-growth and tissue on-growth for stability.

4. An osteoconductive process comprising:

providing an implant, the implant comprising:

a substrate;

a structured surface formed on a portion of the substrate, the structured surface being of the same material as the substrate; and

a biocompatible coating deposited by a selected one of (i) arc evaporation physical vapor deposition and (ii) chemical vapor deposition on at least a fraction of the structured surface, the coating being softer and more biocompatible than the substrate and the structured surface;

testing for the presence of high adhesion between the coating and the structured surface; and

contacting a bone under in vivo conditions with the implant;

wherein the portion of the substrate is fixed with a selected one of tissue in-growth and tissue on-growth for stability.

5. A method of forming a composite coating, the method comprising:

depositing a biocompatible coating on a structured surface that comprises at least a portion of a surface area of a substrate;

wherein depositing the biocompatible coating includes depositing a coating that is more biocompatible than the structured surface;

wherein depositing the biocompatible coating includes depositing a coating that is softer than the structured surface.

6. The method of forming a composite coating according to claim 5 , further comprising:

covering the portion of the surface area of the substrate with a mixture including a plurality of particles, the plurality of particles including a first material; and

sintering the plurality of particles to produce a porous structure;

wherein the biocompatible coating includes a second material that is different from the first material.

7. The method of claim 5 , wherein depositing the biocompatible coating includes depositing a coating that is more biocompatible than the substrate.

8. The method of claim 5 , wherein depositing the biocompatible coating includes depositing a coating that is softer than the substrate.

9. The method of claim 5 , wherein the depositing of the biocompatible coating includes forming the biocompatible coating by a thin film technique.

10. The method of claim 9 , wherein the thin film technique includes at least one deposition process selected from the group consisting of physical vapor deposition and chemical vapor deposition.

11. The method of claim 5 , further comprising, before the step of depositing the biocompatible coating, forming a plurality of undercuts in the structured surface, and wherein depositing the biocompatible coating includes coating the plurality of undercuts in the structured surface.

12. The method of claim 11 , wherein forming a plurality of undercuts includes forming interconnected pores beneath the structured surface, and wherein depositing the biocompatible coating includes coating the interconnected pores.

13. The method of claim 5 , further comprising, before the step of depositing a biocompatible coating, providing the substrate with at least one material selected from the group consisting of carbon-composite, stainless steel, cobalt-chromium, titanium alloy, tantalum, and ceramic.

14. The method of claim 5 , further comprising, before the step of depositing a biocompatible coating, providing the structured surface with a material that includes a plurality of particles that are sintered together to form a continuous porous phase.

15. The method of claim 5 , further comprising, before the step of depositing a biocompatible coating, preparing the structured surface by at least one method selected from the group consisting of sintering, flame spraying, acid etching, grit blasting, casting-in, forging-in, laser texturing, and micromachining.

16. The method of claim 5 , wherein depositing the biocompatible coating includes depositing at least one material selected from the group consisting of titanium, tantalum, carbon, calcium phosphate, zirconium, niobium, hafnium, hydroxyapatite, and tissue in-growth and/or on-growth facilitating proteins.

17. The method of claim 5 , wherein depositing the biocompatible coating includes depositing multi-layers.

18. The method of claim 17 , wherein depositing the biocompatible coating includes depositing nano-layers.

19. The method of claim 5 , further comprising, after the step of depositing a biocompatible coating, treating another portion of the surface area with ion bombardment.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 26, 2021
From: CONSENSUS ORTHOPEDICS, INC.
To: SHALBY ADVANCED TECHNOLOGIES, INC.
Reel/Frame 056364/0864 →
SECURITY INTEREST Recorded Apr 9, 2018
From: CONSENSUS ORTHOPEDICS, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 045474/0451 →
CHANGE OF NAME Recorded Sep 13, 2010
From: HAYES MEDICAL, INC.
To: CONSENSUS ORTHOPEDICS, INC.
Reel/Frame 024973/0648 →
SECURITY AGREEMENT Recorded Apr 7, 2009
From: CONSENSUS ORTHOPEDICS, INC.
To: CROSSROADS DEBT LLC
Reel/Frame 022510/0781 →
Continuity (3)
Continuation 0990131000 · Jul 9, 2001
Continuation 0907950200 · May 14, 1998
Related Publication 20060178751A1 · Aug 10, 2006