Lipid bilayers on nano-templates
View Patent ↗A lipid bilayer on a nano-template comprising a nanotube or nanowire and a lipid bilayer around the nanotube or nanowire. One embodiment provides a method of fabricating a lipid bilayer on a nano-template comprising the steps of providing a nanotube or nanowire and forming a lipid bilayer around the polymer cushion. One embodiment provides a protein pore in the lipid bilayer. In one embodiment the protein pore is sensitive to specific agents.
1. A lipid bilayer on a nano-template, comprising:
a nanotube or nanowire,
a lipid bilayer around said nanotube or nanowire,
a polymer cushion between said nanotube or nanowire and said lipid bilayer, and
a pore in said lipid bilayer.
2. The lipid bilayer on a nano-template of claim 1 wherein said polymer cushion comprises alternating polymer layers around said nanotube or nanowire and including a pore in said lipid bilayer.
3. The lipid bilayer on a nano-template of claim 1 wherein said polymer cushion comprises at least two alternating polymer layers around said nanotube or nanowire and including a pore in said at least two alternating polymer layers.
4. The lipid bilayer on a nano-template of claim 1 wherein said nanotube or nanowire is a single-wall nanotube.
5. The lipid bilayer on a nano-template of claim 1 wherein said nanotube or nanowire is a single-wall carbon nanotube.
6. The lipid bilayer on a nano-template of claim 1 wherein said nanotube or nanowire is a multi-wall nanotube.
7. The lipid bilayer on a nano-template of claim 1 wherein said nanotube or nanowire is a nanowire.
8. The lipid bilayer on a nano-template of claim 1 wherein said nanotube or nanowire is an inorganic nanowire.
9. The lipid bilayer on a nano-template of claim 1 including protein incorporated in said lipid bilayer and a protein pore in said protein incorporated in said lipid bilayer.
10. The lipid bilayer on a nano-template of claim 9 wherein said protein pore in said lipid bilayer is a protein pore that is sensitive to biowarfare agents.
11. The lipid bilayer on a nano-template of claim 9 wherein said protein pore in said lipid bilayer is an oligomeric protein pore in said lipid bilayer.
12. The lipid bilayer on a nano-template of claim 9 wherein said protein pore in said lipid bilayer is a protein pore that is sensitive to specific agents.
13. The lipid bilayer on a nano-template of claim 9 wherein said protein pore in said lipid bilayer is a protein pore that is sensitive to a full spectrum of biowarfare agents including bacteria, viruses and toxins.
14. The lipid bilayer on a nano-template of claim 9 wherein said protein pore in said lipid bilayer is a protein pore that is sensitive to a full spectrum of health related agents including bacteria, viruses and toxins.
15. A one-dimensional lipid bilayer on a nanotube template, comprising:
a nanotube,
a lipid bilayer around said nanotube,
a polymer cushion between said nanotube and said lipid bilayer, and
a protein pore in said lipid bilayer.
16. The one-dimensional lipid bilayer on a nanotube template of claim 15 wherein said polymer cushion comprises at least two alternating polymer layers around said nanotube.
17. The one-dimensional lipid bilayer on a nanotube template of claim 15 wherein said nanotube is a single-wall nanotube.
18. The one-dimensional lipid bilayer on a nanotube template of claim 15 wherein said nanotube is a single-wall carbon nanotube.
19. The one-dimensional lipid bilayer on a nanotube template of claim 15 wherein said nanotube is a multi-wall nanotube.
20. The one-dimensional lipid bilayer on a nanotube template of claim 15 wherein said nanotube is a multi-wall carbon nanotube.
21. The one-dimensional lipid bilayer on a nanotube template of claim 15 including protein incorporated in said lipid bilayer.
22. The one-dimensional lipid bilayer on a nanotube template of claim 15 wherein said protein pore in said lipid bilayer is a protein pore that is sensitive to biowarfare agents.
23. The one-dimensional lipid bilayer on a nanotube template of claim 15 wherein said protein pore in said lipid bilayer is an oligomeric protein pore in said lipid bilayer.