Antimycotic gel having high active compound release
A pharmaceutical preparation comprising a hydrophilic gel-forming agent, water and a compound of the formula I is suitable for the treatment and prophylaxis of dermatomycoses.
1 - 11 . (canceled)
12 . A gel composition comprising:
at least one hydrophilic gel-forming agent;
at least one spreading agent; and
an active component consisting essentially of at least one compound chosen from a compound of formula (I) and physiologically tolerable salts thereof:
wherein R 1 , R 2 , and R 3 , which are identical or different, are a hydrogen atom or alkyl group having 1 to 4 carbon atoms, and R 4 is a saturated hydrocarbon radical having 6 to 9 carbon atoms;
wherein the composition is substantially free of any additional active components, and
wherein the composition is not an emulsion.
13 . A gel composition of claim 12 , wherein the active component consists essentially of 1-hydroxy-4-methyl-6-cyclohexyl-2(1H)pyridone, at least one physiologically tolerable salt thereof, or a mixture thereof.
14 . A gel composition of claim 12 , wherein the active component consists essentially of 1-hydroxy-4-methyl-6-(2,4,4,-trimethylpentyl)-2(1H)pyridone, at least one physiologically tolerable salt thereof, or a mixture thereof.