Intervertebral prosthetic disc
An intervertebral prosthetic disc is disclosed and can be installed within an intervertebral space between a first vertebra and a second vertebra. The intervertebral prosthetic disc can include a first component that can have a first compliant layer that can be configured to engage the first vertebra and at least partially conform to a shape of the first vertebra. Further, the intervertebral prosthetic disc can include a second component that is configured to engage the second vertebra.
1 . An intervertebral prosthetic disc to be installed within an intervertebral space between a first vertebra and a second vertebra, the intervertebral prosthetic disc comprising:
a first component comprising a first compliant layer configured to engage the first vertebra and at least partially conform to a shape of the first vertebra; and
a second component configured to engage the second vertebra.
2 . The intervertebral prosthetic disc of claim 1 , wherein the first compliant layer is at least partially convex.
3 . The intervertebral prosthetic disc of claim 1 , wherein the first compliant layer has a substantially uniform thickness.
4 . The intervertebral prosthetic disc of claim 1 , wherein the first compliant layer has a variable thickness.
5 . The intervertebral prosthetic disc of claim 1 , wherein the first compliant layer comprises an extended use biocompatible material.
6 . The intervertebral prosthetic disc of claim 5 , wherein the extended use biocompatible material is a synthetic polymer, a natural polymer, a bioactive ceramic, compression molded carbon nanofibers, or a combination thereof.
7 . The intervertebral prosthetic disc of claim 6 , wherein the synthetic polymer is a polyurethane material, a polyolefin material, a polyether material, a polyester material, a polycarbonate material, a silicone material, a hydrogel material, or a combination thereof.
8 . The intervertebral prosthetic disc of claim 7 , wherein the polyolefin material is polypropylene, polyethylene, halogenated polyolefin, flouropolyolefin, or a combination thereof.
9 . The intervertebral prosthetic disc of claim 7 , wherein the polyether material is polyetherketone (PEK), polyetheretherketone (PEEK), polyetherketoneketone (PEKK), polyaryletherketone (PAEK), or a combination thereof.
10 . The intervertebral prosthetic disc of claim 7 , wherein the polyester material is polylactide.
11 . The intervertebral prosthetic disc of claim 7 , wherein the polycarbonate material is tyrosine polycarbonate.
12 . The intervertebral prosthetic disc of claim 6 , wherein the natural polymer is collagen, gelatin, fibrin, keratin, chitosan, chitin, hyaluronic acid, albumin, silk, elastin, or a combination thereof.
13 . The intervertebral prosthetic disc of claim 6 , wherein the bioactive ceramic is hydroxyapatite (HA), hydroxyapatite tricalcium phosphate (HATCP), calcium phosphate, calcium sulfate, or a combination thereof.
14 . The intervertebral prosthetic disc of claim 1 , wherein the superior compliant layer, the inferior compliant layer, or a combination thereof includes a biological factor to promote bone growth.
15 . The intervertebral prosthetic disc of claim 14 , wherein the biological factor is a bone morphogenetic protein (BMP), a cartilage-derived morphogenetic protein (CDMP), a platelet derived growth factor (PDGF), an insulin-like growth factor (IGF), a LIM mineralization protein, a fibroblast growth factor (FGF), an osteoblast growth factor, stem cells, or a combination thereof.
16 . The intervertebral prosthetic disc of claim 15 , wherein the stem cells include bone marrow derived stem cells, lipo derived stem cells, or a combination thereof.
17 . The intervertebral prosthetic disc of claim 1 , further comprising a first embedded structure at least partially disposed within the first compliant layer.
18 . The intervertebral prosthetic disc of claim 17 , wherein the first embedded structure is substantially non-resorbable.
19 . The intervertebral prosthetic disc of claim 18 , wherein the first compliant layer is substantially resorbable.
20 . The intervertebral prosthetic disc of claim 17 , wherein the first embedded structure comprises a fabric mesh, a metallic mesh, a polyetheretherketone mesh, a three-dimensional polyester structure, or a combination thereof.
21 . The intervertebral prosthetic disc of claim 1 , wherein the first component further comprises a first keel at least partially covered by the first compliant layer.
22 . The intervertebral prosthetic disc of claim 21 , wherein the first component further comprises a first tooth at least partially covered by the first compliant layer.
23 . The intervertebral prosthetic disc of claim 22 , wherein the first keel, the first tooth, or a combination thereof is configured to at least partially extend through the first compliant layer and engage the first vertebra.
24 . The intervertebral prosthetic disc of claim 1 , wherein the second component comprises a second compliant layer configured to engage the second vertebra and at least partially conform to a shape of the second vertebra.
25 . The intervertebral prosthetic disc of claim 24 , wherein the first compliant layer is at least partially convex and the second compliant layer is at least partially convex.
26 . The intervertebral prosthetic disc of claim 24 , wherein the first compliant layer has a substantially uniform thickness and the second compliant layer has a substantially uniform thickness.
27 . The intervertebral prosthetic disc of claim 24 , wherein the first compliant layer has a variable thickness and the second compliant layer has a variable thickness.
28 . The intervertebral prosthetic disc of claim 24 , further comprising a second embedded structure at least partially disposed within the second compliant layer.
29 . The intervertebral prosthetic disc of claim 24 , further comprising a second keel at least partially covered by the second compliant layer.
30 . The intervertebral prosthetic disc of claim 29 , further comprising a second at least partially covered by the second compliant layer.
31 . The intervertebral prosthetic disc of claim 30 , wherein the second keel, the second tooth, or a combination thereof is configured to at least partially extend through the second compliant layer and engage the second vertebra.
32 . An intervertebral prosthetic disc to be installed within an intervertebral space between an inferior vertebra and a superior vertebra, the intervertebral prosthetic disc comprising:
an inferior support plate having an inferior bearing surface;
an inferior compliant layer disposed on the inferior bearing surface;
an inferior embedded layer disposed within the inferior bearing surface;
a superior support plate having a superior bearing surface;
a superior compliant layer disposed on the superior bearing surface; and
a superior embedded layer disposed within the superior bearing surface.
33 .- 45 . (canceled)
46 . An intervertebral prosthetic disc to be installed within an intervertebral space between an inferior vertebra and a superior vertebra, the intervertebral prosthetic disc comprising:
a superior component, the superior component comprising:
a superior support plate having a superior bearing surface; and
a superior compliant layer disposed on the superior bearing surface;
an inferior component, the inferior component comprising:
an inferior support plate having an inferior bearing surface; and
an inferior compliant layer disposed on the inferior bearing surface; and
a nucleus disposed between the superior component and the inferior component, wherein the nucleus is configured to allow relative motion between the superior component and the inferior component.
47 .- 51 . (canceled)