IP Library › Patent Application 11344862
Patent Application
App. No. 11/344,862

Method for treating hypercholesterolemia with polyallylamine polymers

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Quick Facts
Patent No.
US None
App. No.
11/344,862
Abstract

A method for removing bile salts from a patient that includes administering to the patient a therapeutically effective amount of a non-absorbable amine polymers characterized by a repeat unit having the formula: and salts thereof, where n is a positive integer and x is zero or an integer between 1 and about 4.

Claims (9)

1 - 15 . (canceled)

16 . A method of removing bile salts from a patient comprising administering to said patient a therapeutically effective amount of cross-linked homopolyallylamine,

wherein

said cross-linked homopolyallylamine is cross-linked by a multifunctional crosslinking agent, and

said multifunctional crosslinking agent is present in an amount from 0.5-25% by weight, based upon the combined weight of allylamine repeat units and multifunctional crosslinking agent.

17 . The method of claim 16 wherein said multifunctional crosslinking agent is present in an amount from about 2.5-20% by weight, based upon the combined weight of allylamine repeat units and multifunctional crosslinking agent.

18 . The method of claim 16 , wherein the patient has a serum LDL level of at least 130 mg/dL.

19 . The method of claim 16 , wherein the multifunctional crosslinking agent comprises epichlorohydrin.

20 . The method of claim 16 , wherein the multifunctional crosslinking Agent is epichlorohydrin.