Processing set and methods for processing and treating a biological fluid
View Patent ↗Apparatus, systems and methods are disclosed for treating a biological fluid with light. A container of biological fluid is introduced into a fluid treatment chamber where it is contacted with light provided by one or more light sources in proximity to the fluid treatment chamber. A drawer for holding containers of biological fluid introduces the containers into the chamber. Containers for holding the biological fluid are marked by the apparatus to indicate the status of the treatment.
1. A pre-assembled disposable fluid processing set for use in a photoactivation treatment of a biological fluid comprising:
a first container with a photochemical agent contained therein, said container being adapted for joinder to a source container of biological fluid and being enclosed within an overwrap that is impermeable to light of a selected photoactivating wavelength range;
a second container downstream of and pre-attached to said first container for holding the biological fluid and the photochemical agent during a photoactivation treatment, wherein said container is made of a material that is substantially translucent to light in the photoactivating wavelength range;
a sealed but openable flow path between said first and second containers;
a flow-through device downstream of and pre-attached to said second container for receiving at least said biological fluid from said second container, said device including adsorbent material for removing at least one or both of excess photochemical agent and photoactivation by-products from said biological fluid;
a sealed but openable flow path between said second container and said flow through device;
a container downstream of and pre-attached to said device for receiving said biological fluid from said device.
2. The disposable processing set of claim 1 comprising a tubing segment including an openable flow path for establishing flow communication between said device and said container downstream of said device.
3. The disposable fluid processing set of claim 1 wherein said overwrap is impermeable to light in the UVA wavelength range.
4. The disposable fluid processing set of claim 1 wherein said second container is made of a material that is substantially translucent to photoactivating light in the UVA range.
5. The disposable processing set of claim 1 further including a holder for temporarily holding at least said device.
6. The disposable processing set of claim 1 including a holder for temporarily holding said device and container downstream of said device.
7. The disposable fluid processing set of claim 1 wherein said openable flow paths include frangible connectors.
8. The disposable fluid processing set of claim 7 wherein said openable flow paths comprise plastic tubes with said frangible connectors disposed therein.