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Patent Application
App. No. 11/354,210

Novel human secreted proteins and polynucleotides encoding the same

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Patent No.
US None
App. No.
11/354,210
Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims (6)

1 . An isolated nucleic acid molecule that encodes the amino acid sequence of SEQ ID NO:2, 5, 7, 9, 11, 14, 16, 18, 20, 22, 24, 27, 29, 32, 34, 36, 38, 40, 42, 44, 46, 48, 51, 54, 56, 59, 61, 63, 65, 68, 70, 73, 75, 77, 80, 82, 85, 88, 91, 93, 95, 97, 99, 101, 103, 105, 107, 109, 111, 113, 115, 117, 119, 121, 123, 125, 127, 130, 132, 134, or 136.

2 . The isolated nucleic acid molecule of claim 1 , wherein said nucleic acid molecule comprises the nucleotide sequence of SEQ ID NO:1, 4, 6, 8, 10, 13, 15, 17, 19, 21, 23, 26, 28, 31, 33, 35, 37, 39, 41, 43, 45, 47, 50, 53, 55, 58, 60, 62, 64, 67, 69, 72, 74, 76, 79, 81, 84, 87, 90, 92, 94, 96, 98, 100, 102, 104, 106, 108, 110, 112, 114, 116, 118, 120, 122, 124, 126, 129, 131, 133, or 135.

3 . An expression vector comprising the isolated nucleic acid molecule of claim 1 .

4 . An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:2, 5, 7, 9, 11, 14, 16, 18, 20, 22, 24, 27, 29, 32, 34, 36, 38, 40, 42, 44, 46, 48, 51, 54, 56, 59, 61, 63, 65, 68, 70, 73, 75, 77, 80, 82, 85, 88, 91, 93, 95, 97, 99, 101, 103, 105, 107, 109, 111, 113, 115, 117, 119, 121, 123, 125, 127, 130, 132, 134, or 136.

5 . An antibody that selectively binds a polypeptide drawn from the group consisting of: SEQ ID NO: 2, 5, 7, 9, 11, 14, 16, 18, 20, 22, 24, 27, 29, 32, 34, 36, 38, 40, 42, 44, 46, 48, 51, 54, 56, 59, 61, 63, 65, 68, 70, 73, 75, 77, 80, 82, 85, 88, 91, 93, 95, 97, 99, 101, 103, 105, 107, 109, 111, 113, 115, 117, 19, 121, 123, 125, 127, 130, 132, 134, and 136.

6 . An oligonucleotide that inhibits the expression of a nucleic acid molecule that encodes an amino acid sequence drawn from the group consisting of: SEQ ID NO: 2, 5, 7, 9, 11, 14, 16, 18, 20, 22, 24, 27, 29, 32, 34, 36, 38, 40, 42, 44, 46, 48, 51, 54, 56, 59, 61, 63, 65, 68, 70, 73, 75, 77, 80, 82, 85, 88, 91, 93, 95, 97, 99, 101, 103, 105, 107, 109, 111, 113, 115, 117, 119, 121, 123, 125, 127, 130, 132, 134, and 136.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Sep 14, 2020
From: BIOPHARMA CREDIT PLC
To: LEXICON PHARMACEUTICALS, INC.
Reel/Frame 053767/0445 →
SECURITY INTEREST Recorded Dec 20, 2017
From: LEXICON PHARMACEUTICALS, INC.
To: BIOPHARMA CREDIT PLC
Reel/Frame 044958/0377 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 16, 2006
From: DONOHO, GREGORY; FRIDDLE, CARL JOHAN; FRIEDRICH, GLENN; HILBUN, ERIN; HU, YI; MATHUR, BRIAN; MIRANDA, MARICAR; NEHLS, MICHAEL C.; NGUYEN, NGHI D.; SANDS, ARTHUR T.; SCOVILLE, JOHN; TURNER, JR., C. ALEXANDER; WALKE, D. WADE; WANG, XIAOMING; WATTLER, FRANK; WILGANOWSKI, NATHANIEL L.; XIE, QIONGSHU; YU, XUANCHUAN; ZAMBROWICZ, BRIAN
To: LEXICON GENETICS INCORPORATED
Reel/Frame 018210/0493 →