IP Library Granted Patent US 9,271,902
Granted Patent B2
US 9,271,902 · App. 11/355,924 · Granted Mar 1, 2016

Whitening system capable of delivering effective whitening action

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Quick Facts
Patent No.
US 9,271,902
App. No.
11/355,924
Granted
Mar 1, 2016
Kind
B2
Abstract

The invention provides a foamable composition for tooth bleaching which can be a one- or two-component system. The system has at least one peroxide compound, and at least one foaming agent. The composition can also contain at least one source of calcium, strontium and mixtures thereof, at least one de-sensitizing agent and at least one source of phosphate. The composition can produce a longer-lasting, collapsible foam structure with enhanced whitening action. The foamable composition can also be a one-component multi-phase system. A two-component composition can be packed in a two-compartment syringe. The syringe can also be fitted with a dispensing tip which may or may not have a static mixer.

Claims (37)

1. A liquid collapsible foam two-component tooth whitening composition comprising:

a first liquid component comprising an acid including a tartaric acid and at least one peroxide compound, and at least one carrier; and

a second liquid component comprising:

an effervescent compound that includes a carbonate; and,

at least one foaming agent;

wherein the foaming agent includes

hydroxyethyl cellulose; and

either the first or second components further including:

eugenol;

wherein the first and second liquid components are structurally configured to be maintained separated before use and are configured to be combined with each other just prior to use to form a liquid collapsible foam, with gas generated therein, the collapsible foam having a half life of about 2 to about 30 minutes; wherein the liquid collapsible foam is configured to be applied to the surface of the teeth directly; and wherein the foam collapses into a liquid.

2. The liquid collapsible foam composition of claim 1 wherein said peroxide compound comprises metal ion free peroxide compounds.

3. The liquid collapsible foam composition of claim 1 wherein said peroxide compound is selected from the group consisting of hydrogen peroxide, urea peroxide (carbamide peroxide), calcium peroxide, glyceryl peroxide, benzoyl peroxide and mixtures thereof.

4. The liquid collapsible foam composition of claim 1 wherein the peroxide compound is present from about 1% by weight to about 45% by weight of the first component.

5. The liquid collapsible foam composition of claim 1 wherein the peroxide compound is present from about 5% by weight to about 35% by weight of the first component.

6. The liquid collapsible foam composition of claim 1 wherein said foaming agent further comprises one or more selected from the group consisting of surfactants, alkali metal carbonates and bicarbonates, gas and mixtures thereof.

7. The liquid collapsible foam composition of claim 6 wherein said surfactant comprises ionic and non-ionic surfactants.

8. The liquid collapsible foam composition of claim 7 wherein said surfactant is selected from the group consisting of sodium lauryl sulfate, phospholipids, low viscosity poloxamers, and polysorbates.

9. The liquid collapsible foam composition of claim 1 wherein said foaming agent comprises a hydrophilic and a hydrophobic component.

10. The liquid collapsible foam composition of claim 1 wherein said first component further comprises an acidic compound selected from the group consisting of water soluble carboxylic acids, nitric acid, phosphoric acids and mixtures thereof.

11. The liquid collapsible foam composition of claim 1 further comprising a foam stabilizer selected from group consisting of acidic compounds, xanthan gums, hydroxyethyl cellulose, low viscosity thickeners, and mixtures thereof.

12. The liquid collapsible foam composition of claim 1 further comprising an ingredient selected from the group consisting of peroxide stabilizers, emulsifiers, flavorings, coloring agents, anti-plaque agents, anti-staining compounds, emollients, preservatives, antioxidants, chelating agents, tonicity modifiers, spreading agents, alcohols, pH adjusting agents, water soluble lubricants, and mixtures thereof.

13. The liquid collapsible foam composition of claim 1 further comprising at least one source of phosphate in the first component and at least one source of calcium, strontium, or combinations thereof in the second component.

14. The liquid collapsible foam composition of claim 13 wherein the source of phosphate acts as a pH adjuster.

15. The liquid collapsible foam composition of claim 1 wherein said first component comprises at least one peroxide compound in an aqueous solution and at least one peroxide stabilizer in the form of an ion scavenger; said second component comprises at least one foaming agent and at least one peroxide activator, wherein said activator promotes the rapid decomposition of the peroxide compound and additional foaming action not related to the foaming agent.

16. A liquid collapsible foam multi-component composition comprising:

at least one peroxide compound, and

at least one carrier; and,

at least one foaming agent;

wherein the foaming agent includes:

hydroxyethyl cellulose; and

further including:

tartaric acid

an effervescent compound that includes a carbonate; and

eugenol;

wherein the peroxide compound with tartaric acid and the effervescent compound that includes a carbonate with the foaming agent are configured separated before use and are configured to be combined just prior to use to generate a collapsible foam with a gas generated therewithin and wherein the collapsible foam generated has a half life of about 2 to about 30 minutes; wherein the collapsible foam is applied to the surface of the teeth directly; and wherein the foam collapses into a liquid.

17. The liquid collapsible foam composition of claim 16 wherein a foam is generated through mechanical action.

18. The liquid collapsible foam composition of claim 16 wherein said carrier comprises an ingredient selected form the group consisting of an alcohol, a peroxide activator, a peroxide stabilizer, a foaming agent, a foam stabilizer, a peroxide stabilizer, an emulsifier, flavorings, a coloring agent, an anti-plaque agent, an anti-staining compound, emollients, a preservative, an antioxidant, a chelating agent, tonicity modifiers, a spreading agent, an alcohol, a pH adjusting agent, water soluble lubricants, and mixtures thereof.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 21, 2008
From: LAB39, LLC
To: GRINRX CORPORATION
Reel/Frame 021870/0567 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 18, 2008
From: GINIGER, MARTIN S; SPAID, MATTHEW S
To: LAB39 LLC
Reel/Frame 021847/0481 →