Patent Application
App. No. 11/357,028
Urate oxidase
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Abstract
The present invention relates, in general, to urate oxidase (uricase) proteins and nucleic acid molecules encoding same. In particular, the invention relates to uricase proteins which are particularly useful as, for example, intermediates for making improved modified uricase proteins with reduced immunogenicity and increased bioavailability.
Claims (1)
1 . A protein comprising a recombinant uricase protein of a mammalian species which has been modified to insert one or more lysine residues.
Assignments (3)
RELEASE OF SECURITY INTEREST
Recorded Oct 6, 2023
From: CITIBANK, N.A.
To: HORIZON THERAPEUTICS USA, INC.
Reel/Frame 065178/0965 →
PATENT SECURITY AGREEMENT
Recorded Sep 16, 2016
From: HORIZON PHARMA RHEUMATOLOGY LLC (FORMERLY KNOWN AS CREALTA PHARMACEUTICALS LLC)
To: CITIBANK, N.A., AS COLLATERAL AGENT
Reel/Frame 040059/0007 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jul 31, 2009
From: HERSHFIELD, MICHAEL S.; KELLY, SUSAN J.
To: DUKE UNIVERSITY
Reel/Frame 023037/0222 →