IP Library Granted Patent US 8,027,718
Granted Patent B2
US 8,027,718 · App. 11/370,967 · Granted Sep 27, 2011

Regional anesthetic

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Quick Facts
Patent No.
US 8,027,718
App. No.
11/370,967
Granted
Sep 27, 2011
Kind
B2
Abstract

A method and apparatus are disclosed for anesthetizing a region of a patient's body. The method includes identifying a target nerve which, upon activation, anesthetizes a region of a patient's body including a surgical site. The target nerve is located and an active site of a nerve blocking apparatus is placed in proximity to the nerve. The nerve blocking apparatus is activated to block neural propagation along the nerve. The activation of the nerve blocking apparatus is maintained during a surgical procedure at the surgical site.

Claims (53)

1. A method of anesthetizing a region of a patient's body, comprising:

identifying a target nerve which, upon anesthetization, anesthetizes a region of a patient's body including a surgical site;

locating the target nerve;

placing an electrode of a nerve blocking apparatus in proximity to the nerve;

connecting the electrode to an external power source via a conductive path inserted through the patient's skin;

anesthetizing the region of the patient's body by activating the electrode at a frequency of at least 5,000 Hz to block neural propagation of afferent pain signals along the nerve; and

retaining the activated electrode of the nerve blocking apparatus in proximity to the nerve during a surgical procedure at the site.

2. The method of claim 1 wherein activating the electrode includes creating a field near the desired target location with parameters selected to at least partially block neural activity within the field.

3. The method of claim 1 wherein locating the target nerve includes activating an electrical stimulation at a suspected location of the nerve and observing a physiologic response to the stimulation confirming the suspected location.

4. The method of claim 3 wherein locating the target nerve includes placing a needle through a skin of the patient with the electrode positioned on the needle and advanced to the suspected location, and activating the electrode with a stimulation signal selected to induce action potentials in a nerve in close proximity to the electrode.

5. The method of claim 1 , further comprising advancing the electrode through a needle to the nerve and connecting the electrode to a source of a nerve blocking signal.

6. The method of claim 5 , further comprising withdrawing the needle while leaving the electrode at the nerve.

7. The method of claim 1 wherein the electrode is carried by a catheter having a deployable, tissue-penetrating tip, and wherein placing the electrode includes advancing the catheter through the patient's tissue while the tip projects from the catheter, and withdrawing the tip into the catheter after penetrating through the patient's tissue.

8. The method of claim 7 wherein locating the target nerve includes activating the electrode in accordance with a first mode to stimulate adjacent tissue, and wherein anesthetizing the region of the patient's body includes activating the electrode in accordance with a second mode different than the first mode.

9. The method of claim 1 wherein placing an electrode includes delivering the electrode percutaneously.

10. A method for treating a patient, comprising:

identifying a target nerve which, upon anesthetization, anesthetizes a region of a patient's body including a surgical site;

locating the target nerve;

placing an electrode of a nerve blocking apparatus in proximity to the nerve;

connecting the electrode to an external power source via a conductive path inserted through the patient's skin;

anesthetizing the region of the patient's body by activating the electrode at a frequency of at least 5,000 Hz to block neural propagation of afferent pain signals along the nerve;

retaining the activated electrode of the nerve blocking apparatus in proximity to the nerve during a surgical procedure at the surgical site; and

blocking neural propagation of afferent pain signals after the surgical procedure by activating the electrode at a frequency of at least 5,000 Hz after the surgical procedure.

11. The method of claim 10 wherein blocking neural propagation of afferent pain signals after the surgical procedure includes blocking the pain signals during patient recovery from surgery.

12. The method of claim 10 wherein blocking neural propagation of afferent pain signals after the surgical procedure includes blocking the pain signals to treat chronic patient pain.

13. The method of claim 10 wherein placing an electrode includes delivering the electrode percutaneously.

14. The method of claim 10 wherein placing an electrode includes placing the active electrode surgically.

15. The method of claim 10 wherein anesthetizing the region of the patient's body includes anesthetizing the region during knee surgery.

16. The method of claim 10 wherein blocking neural propagation of afferent pain signals after the surgical procedure includes blocking neural propagation of afferent pain signals for days after the surgical procedure.

17. The method of claim 10 , further comprising:

implanting a pulse generator; and

coupling the pulse generator to the electrode.

18. A method for treating a patient, comprising:

identifying a target nerve which, upon anesthetization, anesthetizes a region of a patient's body including a surgical site;

locating the target nerve;

placing an electrode of a nerve blocking apparatus in proximity to the nerve;

connecting the electrode to an external power source via a conductive path inserted through the patient's skin;

anesthetizing the region of the patient's body by activating the electrode at a frequency of at least 5,000 Hz to block neural propagation of afferent pain signals along the nerve;

retaining the activated electrode of the nerve blocking apparatus in proximity to the nerve during a surgical procedure at the surgical site; and

blocking neural propagation of afferent pain signals after the surgical procedure by activating an electrode of the nerve blocking apparatus at a frequency of at least 5,000 Hz after the surgical procedure to treat chronic pain experienced by the patient.

19. The method of claim 18 wherein the nerve blocking apparatus includes multiple electrodes, and wherein activating the electrode in proximity to the nerve includes activating a first electrode, and wherein activating an electrode after the surgical procedure to treat chronic pain experienced by the patient includes activating a second electrode.

20. The method of claim 19 wherein at least one of the electrodes is positioned at the patient's spinal column.

21. The method of claim 19 wherein at least one of the electrodes is positioned in the patient's epidural space.

22. The method of claim 19 , further comprising:

implanting a pulse generator; and

coupling the pulse generator to the second electrode.

23. The method of claim 18 wherein placing an electrode includes delivering the electrode percutaneously.

24. The method of claim 18 wherein placing an electrode includes placing the electrode surgically.

25. The method of claim 18 wherein anesthetizing the region of the patient's body includes anesthetizing the region during knee surgery.

26. The method of claim 18 wherein blocking neural propagation of afferent pain signals after the surgical procedure includes blocking neural propagation of afferent pain signals for days after the surgical procedure.

27. The method of claim 18 , further comprising:

implanting a pulse generator; and

coupling the pulse generator to the electrode.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Apr 4, 2025
From: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT
To: NEVRO CORP.
Reel/Frame 070743/0001 →
PATENT SECURITY AGREEMENT Recorded Dec 1, 2023
From: NEVRO CORP.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT
Reel/Frame 065744/0302 →
RELEASE OF SECURITY INTEREST Recorded Jun 27, 2016
From: CRG SERVICING LLC
To: NEVRO CORP.
Reel/Frame 039168/0890 →
ASSIGNMENT AGREEMENT (REAFFIRMATION) Recorded Jun 13, 2016
From: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
To: CRG SERVICING LLC,
Reel/Frame 038984/0865 →
SECURITY INTEREST Recorded Dec 12, 2014
From: NEVRO CORP.
To: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
Reel/Frame 034619/0546 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 1, 2006
From: SPINNER, ROBERT J.; MARTIN, DAVID P.; CONRAD, TIMOTHY R.
To: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Reel/Frame 018140/0740 →