IP Library Granted Patent US 7,674,482
Granted Patent B2
US 7,674,482 · App. 11/386,325 · Granted Mar 9, 2010

Method and compositions for potentiating pharmaceuticals with amino acid based medical foods

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Quick Facts
Patent No.
US 7,674,482
App. No.
11/386,325
Granted
Mar 9, 2010
Kind
B2
Abstract

The methods and compositions for potentiating pharmaceuticals with amino acid based medical foods provides improved cognitive function; induced and maintained sleep; reduced pain, inflammation, blood pressure, anxiety, asthma, duration of viral infection, insulin resistance, and appetite; and treated depression. The amino acid based medical foods, co-packed with at least one selected pharmaceutical, potentiate the pharmaceutical by enhancing the production of neurotransmitters through the oral administration of neurotransmitter precursors, along with natural plant and animal substances that stimulate uptake of the neurotransmitter precursors, cause release of neurotransmitters, cause disinhibition of the neuronal brake, and activate adenylate cyclase in order to avoid tachyphylaxis and prevent pharmacologic tolerance.

Claims (22)

1. A co-packed medical food combination for producing acetylcholine and serotonin for reducing sleep latency, preventing early awakenings and ameliorating depression comprising a first and a second composition:

a first composition comprising:

from about 20% to about 65%, based on the total weight of said first composition, of choline;

from about 0.7% to about 2.1%, based on the total weight of said first composition, of acetylcarnitine;

from about 1.8% to about 5.3%, based on the total weight of said first composition, of 5-hydroxytryptophan;

from about 1.8% to about 5.3%, based on the total weight of said first composition, of ginkgo biloba;

from about 3.5% to about 10.5%, based on the total weight of said first composition, of glutamate;

from about 14% to about 42%, based on the total weight of said first composition, of cocoa;

from about 7% to about 21%, based on the total weight of said first composition, of dextrose; and

a second composition comprising:

from about 25 mg to about 75 mg of trazadone, wherein said first composition potentiates said second composition for said reducing sleep latency, preventing early awakenings and ameliorating depression.

2. A co-packed medical food combination for producing acetylcholine and serotonin for preventing early awakenings and to ameliorate depression comprising a first and a second composition:

a first composition comprising:

from about 20% to about 65%, based on the total weight of said first composition, of choline;

from about 0.7% to about 2.5%, based on the total weight of said first composition, of acetylcarnitine;

from about 1.7% to about 5.5%, based on the total weight of said first composition, of 5-hydroxytryptophan;

from about 1.7% to about 5.5%, based on the total weight of said first composition, of ginkgo biloba;

from about 3% to about 15%, based on the total weight of said first composition, of glutamate;

from about 14% to about 45%, based on the total weight of said first composition, of cocoa;

from about 7% to about 25%, based on the total weight of said first composition, of dextrose; and

a second composition comprising:

from about 25 mg to about 75 mg of trazadone, wherein said first composition potentiates said second composition for said preventing early awakenings and to ameliorate depression.

Assignments (2)
CORRECTION BY DECLARATION FOR PATENT NUMBERS 7,582,315 AND 7,674,482 RECORDED AT REEL NUMBER 036053 AND FRAME NUMBERS 0700-0702 Recorded Apr 8, 2016
From: TARGETED MEDICAL PHARMA, INC.
To: TARGETED MEDICAL PHARMA, INC.
Reel/Frame 038389/0746 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 30, 2015
From: SHELL, WILLIAM
To: WILLIAM SHELL SURVIVORS TRUST
Reel/Frame 036053/0700 →