IP Library Granted Patent US 7,758,553
Granted Patent B2
US 7,758,553 · App. 11/397,047 · Granted Jul 20, 2010

Drop dispenser for the delivery of uniform droplets of viscous liquids

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Quick Facts
Patent No.
US 7,758,553
App. No.
11/397,047
Granted
Jul 20, 2010
Kind
B2
Abstract

A drop dispenser has a substantially conical sleeve member with a narrow upper end and a wide lower end. Centrally located at the apex of the upper end of the sleeve member is an aperture which has an inner diameter and is circumscribed by a raised ridge. The aperture and the ridge form a nozzle. The interior space of the substantially conical sleeve member forms a substantially conical chamber between the narrow upper end and wide lower end of the sleeve member. The nozzle is in liquid communication with the chamber through the aperture. The drop dispenser may have external threads at the lower end of the sleeve member for engaging a cap having a protuberance centrally located at its internal top end for hermetically engaging the aperture of the nozzle when the cap fully engages the sleeve member.

Claims (22)

1. A drop dispenser for dispensing a viscous liquid, comprising a substantially conical sleeve member having an upper end, a lower end, and an aperture centrally located at the apex of the upper end;

wherein the lower end of the sleeve member is wider than the upper end of the sleeve member;

wherein the aperture has an inner diameter and is circumscribed by a raised ridge having an outer diameter, an inner diameter the same as the inner diameter of the aperture, and a thickness, the aperture and raised ridge forming a nozzle at the upper end of the sleeve member;

wherein the outer diameter of the raised ridge has a smaller diameter than an outer diameter of an upper surface of the upper end of the sleeve member;

the thickness of the ridge extends parallel to a longitudinal axis of the drop dispenser;

wherein the outer diameter of the raised ridge extends parallel to the inner diameter of the aperture along a portion of the thickness of the raised ridge;

wherein an interior space of the substantially conical sleeve member forms a substantially conical chamber between the upper end and the lower end,

wherein the nozzle is in liquid communication with the chamber by way of the aperture; and

wherein the inner diameter of the aperture is from about 0.010 to about 0.060 inches, the outer diameter of the raised ridge is the inner diameter plus about from 0.020 to about 0.060 inches, and the thickness of the entire ridge is from about 0.005 to about 0.040 inches;

the conical chamber has a volume that is at least 5 times the volume of a drop formed from the drop dispenser;

the conical chamber has a volume of from 500 microliters to about 1000 microliters;

the lower end of the sleeve member comprises means for engaging a container;

the container comprises a resilient material;

the container comprises one of a squeezable bottle, a squeezable vial, a squeezable tube, and a syringe;

the nozzle is dimensioned and configured for delivering drops of the viscous liquid with each drop having a volume of about 25-40 microliters, the viscous liquid having a viscosity from about 100 to about 10,000 centipoises.

2. The drop dispenser of claim 1 , wherein the inner diameter of the aperture is about 0.050 inches.

3. The drop dispenser of claim 1 , wherein the inner diameter of the aperture is about 0.050 inches, the outer diameter of the raised ridge is the inner diameter plus about 0.040 inches, and the thickness of the ridge is about 0.010 inches.

4. The drop dispenser of claim 1 , wherein the lower end of the sleeve member has an external thread; further comprising a cap having an internal thread engageable with the external thread, and a protuberance centrally located at an internal top end for hermetically engaging the nozzle when the cap is engaged with the external thread.

5. The drop dispenser of claim 4 , further comprising a breakaway cover encompassing the cap.

6. The drop dispenser of claim 1 , wherein the drop dispenser comprises one of polypropylene, blended polypropylene-polyethylene copolymers, polyvinyl chloride (“PVC”), polyethylene terepthalate (“PET”), polytetrafluoroethylene, acrylonitrile-butadiene-styrene (“ABS”), polystyrene, polycarbonate, polyamides, and a polyester.

7. The drop dispenser of claim 1 , wherein the viscous liquid has a viscosity from about 1,000 to about 5,000 centipoises.

8. The drop dispenser of claim 1 , wherein the inner diameter of the aperture is about 0.050 inches, the outer diameter of the raised ridge is about 0.090 inches, and thickness of the ridge is about 0.025 inches.

Assignments (19)
MERGER Recorded Apr 19, 2021
From: WOLVERINE BIOSCIENCES, LLC
To: WOODSTOCK STERILE SOLUTIONS, INC.
Reel/Frame 055955/0975 →
PATENT SECURITY AGREEMENT Recorded Apr 9, 2021
From: WOLVERINE BIOSCIENCES, LLC
To: CERBERUS BUSINESS FINANCE AGENCY, LLC, AS COLLATERAL AGENT
Reel/Frame 055886/0460 →
CONVERSION Recorded Apr 5, 2021
From: R.P. SCHERER TECHNOLOGIES, INC.
To: R.P. SCHERER TECHNOLOGIES, LLC
Reel/Frame 055820/0039 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 5, 2021
From: CATALENT PHARMA SOLUTIONS, LLC; R.P. SCHERER TECHNOLOGIES, LLC; CATALENT PHARMA SOLUTIONS, INC.
To: WOLVERINE BIOSCIENCES, LLC
Reel/Frame 055821/0051 →
PATENT SECURITY AGREEMENT Recorded Mar 31, 2021
From: CATALENT USA WOODSTOCK, INC.
To: CERBERUS BUSINESS FINANCE AGENCY, LLC, AS THE COLLATERAL AGENT
Reel/Frame 055778/0019 →
PARTIAL RELEASE OF SECURITY INTEREST Recorded Mar 23, 2021
From: JPMORGAN CHASE BANK, N.A.
To: R.P. SCHERER TECHNOLOGIES, LLC (F/K/A R.P. SCHERER TECHNOLOGIES, INC.); CATALENT PHARMA SOLUTIONS, LLC; CATALENT USA WOODSTOCK, INC. (FORMERLY KNOWN AS CARDINAL HEALTH 400, INC.)
Reel/Frame 055681/0049 →
NOTICE OF SUCCESSION OF AGENCY Recorded May 17, 2019
From: MORGAN STANLEY SENIOR FUNDING, INC.
To: JPMORGAN CHASE BANK, N.A.
Reel/Frame 049217/0981 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2018
From: INSITE VISION INCORPORATED
To: SUN PHARMA GLOBAL FZE
Reel/Frame 044883/0912 →
RELEASE OF SECURITY INTEREST Recorded Nov 18, 2015
From: U.S. BANK NATIONAL ASSOCIATION
To: INSITE VISION INCORPORATED
Reel/Frame 037065/0458 →
RELEASE OF SECURITY INTEREST Recorded Nov 17, 2015
From: RANBAXY, INC.
To: INSITE VISION INCORPORATED
Reel/Frame 037064/0929 →
SECURITY INTEREST Recorded Sep 17, 2015
From: INSITE VISION INCORPORATED
To: RANBAXY, INC.
Reel/Frame 036584/0229 →
RELEASE OF SECURITY INTEREST Recorded Sep 16, 2015
From: QLT INC.
To: INSITE VISION, INC.
Reel/Frame 036578/0154 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jun 11, 2015
From: QLT INC.
To: INSITE VISION INCORPORATED
Reel/Frame 035889/0478 →
SECURITY INTEREST Recorded Oct 13, 2014
From: INSITE VISION INCORPORATED
To: U.S. BANK NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 033975/0433 →
CHANGE OF NAME Recorded Jul 24, 2007
From: CARDINAL HEALTH 400, INC.; CARDINAL HEALTH 406, LLC; CARDINAL HEALTH 409, INC.; CARDINAL HEALTH 421, INC.; CARDINAL HEALTH PTS, LLC
To: CATALENT USA WOODSTOCK, INC.; CATALENT USA PACKAGING, LLC; CATALENT PHARMA SOLUTIONS, INC.; CATALENT USA PAINTBALL, INC.; CATALENT PHARMA SOLUTIONS, LLC
Reel/Frame 019588/0622 →
SECURITY AGREEMENT Recorded May 22, 2007
From: PTS ACQUISITION CORP.; PTS INTERMEDIATE HOLDINGS LLC; CARDINAL HEALTH 400, INC.; CARDINAL HEALTH 406, LLC; CARDINAL HEALTH 421, INC.; CARDINAL HEALTH PTS, LLC; R.P. SCHERER TECHNOLOGIES, INC.; GLACIER CORPORATION; CARDINAL HEALTH 409, INC.
To: MORGAN STANLEY SENIOR FUNDING, INC.
Reel/Frame 019323/0302 →
LICENSE Recorded Mar 1, 2007
From: INSITE VISION INCORPORATED
To: INSPIRE PHARMACEUTICALS, INC.
Reel/Frame 018942/0533 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 3, 2006
From: POISSON, PATRICK
To: R.P. SCHERER TECHNOLOGIES, INC.
Reel/Frame 017715/0701 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 3, 2006
From: BOWMAN, LYLE M.
To: INSITE VISION INCORPORATED
Reel/Frame 017712/0380 →