IP Library › Patent Application 11405679
Patent Application
App. No. 11/405,679

Method for preventing or treating ischemia-or hemorrhage-induced brain damage using a macrolide compound

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Quick Facts
Patent No.
US None
App. No.
11/405,679
Abstract

Macrolide compound, such as a tacrolimus analogue is provided for use as a neuroprotective agent, particularly, for preventing or treating acute or chronic cerebral neurodegenerative diseases.

Claims (6)

1 . A method for preventing or treating brain damage caused by ischemia or hemorrhage, which comprises administering the compound (I) of the following formula:

to mammals.

2 . The method of claim 1 , in which the brain damage caused by ischemia or hemorrhage is cerebral infarction.

3 . The method of claim 1 , in which the brain damage caused by ischemia or hemorrhage is the result of hemorrhagic infarct, head injury, subarachnoid hemorrhage, intracerebral hemorrhage, cerebral thrombosis, cerebral embolism, cardiac arrest, stroke, or transient ischemic attacks (TIA).

4 . The method of claim 1 , in which the brain damage caused by ischemia or hemorrhage is the result of stroke.

5 . The method of claim 1 , in which the brain damage caused by ischemia or hemorrhage is the result of chronic stroke.