IP Library › Granted Patent US 7,521,217
Granted Patent B2
US 7,521,217 · App. 11/409,487 · Granted Apr 21, 2009

Carbonic anhydrase having increased stability under high temperature conditions

Assignee: CO2 Solution, Inc.
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Quick Facts
Patent No.
US 7,521,217
App. No.
11/409,487
Granted
Apr 21, 2009
Kind
B2
Abstract

The present invention relates to polynucleotide and polypeptide sequences of carbonic anhydrase variants having increased stability under high temperature conditions compared to native carbonic anhydrase.

Claims (3)

1. A modified carbonic anhydrase polypeptide having increased thermal stability compared to unmodified native carbonic anhydrase, said modified carbonic anhydrase comprising the amino acid sequence of SEQ ID NO: 1, with at least two amino acid substitutions selected from the group consisting of Leu100His, Gln136Tyr, Lys153Leu, and Ala247Thr.

2. The modified carbonic anhydrase of claim 1 , consisting of the amino acid sequence of SEQ ID NO: 11.

3. The modified carbonic anhydrase of claim 1 , being encoded by the nucleic acid sequence of SEQ ID NO: 21.

Assignments (2)
CHANGE OF NAME Recorded Jan 23, 2012
From: CO2 SOLUTION INC.
To: CO2 SOLUTIONS INC.
Reel/Frame 027575/0335 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 5, 2006
From: DAIGLE, RICHARD; DESROCHERS, MARC
To: CO2 SOLUTION, INC.
Reel/Frame 018066/0717 →
Continuity (2)
Provisional Application 6067334500 · Apr 21, 2005
Related Publication 20060257990A1 · Nov 16, 2006