Human cDNAs and proteins and uses thereof
The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be used in screening and diagnosis assays for abnormal GENSET expression and/or biological activity and for screening compounds that may be used in the treatment of GENSET-related disorders.
1 . A composition of matter comprising:
a) an isolated polynucleotide encoding the polypeptide of SEQ ID NO: 6;
b) an expression vector comprising a polynucleotide encoding the polypeptide of SEQ ID NO: 6; or
c) a recombinant host cell comprising a polynucleotide encoding the polypeptide of SEQ ID NO: 6.
2 . The composition of matter according to claim 1 , wherein said polynucleotide comprises SEQ ID NO: 5.
3 . A method of making a polypeptide, said method comprising
a) providing a population of host cells comprising the polynucleotide of claim 1;
b) culturing said population of host cells under conditions conducive to the production of a polypeptide comprising SEQ ID NO: 6; and
c) purifying said polypeptide from said population of host cells.