Recombinant SP-A for the treatment or prevention of pulmonary infection and inflammation
Recombinant surfactant protein A and medicament compositions based thereon are useful for the prevention or treatment of pulmonary infection and inflammation.
1 .- 17 . (canceled)
18 . A lipid-free pharmaceutical composition in powder form comprising a pharmaceutically acceptable active component and a suitable carrier therefore, wherein the active component comprises recombinant surfactant protein A (rSP-A).
19 . The pharmaceutical composition of claim 18 , wherein the rSP-A is obtained by expression of a genomic sequence coding for SP-A in a suitable expression system.
20 . The pharmaceutical composition of claim 18 , wherein the rSP-A is obtained by expression of a cDNA coding for SP-A in a suitable expression system.
21 . An article of manufacture comprising packaging material and the pharmaceutical composition according to claim 18 contained within the packaging material, wherein the packaging material comprises a label or package insert which indicates that the active component is useful for treating a pulmonary microbial infection or inflammation.