IP Library › Granted Patent US 7,449,579
Granted Patent B1
US 7,449,579 · App. 11/416,667 · Granted Nov 11, 2008

Detection of electrophilic and nucleophilic chemical agents

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 7,449,579
App. No.
11/416,667
Granted
Nov 11, 2008
Kind
B1
Abstract

A “real time” method for detecting electrophilic and nucleophilic species generally by employing tunable, precursor sensor materials that mimic the physiological interaction of these agents to form highly florescent berberine-type alkaloids that can be easily and rapidly detected. These novel precursor sensor materials can be tuned for reaction with both electrophilic (chemical species, toxins) and nucleophilic (proteins and other biological molecules) species.

Claims (2)

1. A precursor sensor molecule having the generic formula:

wherein, R is thio-, hydroxy-, a protected ether or carbonyldiimidizole and R′ is methylene dioxy.

Assignments (3)
CHANGE OF NAME Recorded Feb 7, 2018
From: SANDIA CORPORATION
To: NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC
Reel/Frame 045286/0599 →
CONFIRMATORY LICENSE Recorded Aug 10, 2006
From: SANDIA CORPORATION
To: ENERGY, U.S. DEPARTMENT OF
Reel/Frame 018090/0863 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 22, 2006
From: MCELHANON, JAMES R.; SHEPODD, TIMOTHY J.
To: SANDIA NATIONAL LABORATORIES
Reel/Frame 017837/0820 →