Alkaline detergent for automatic analyzer, washing method for automatic analyzer, and automatic analyzer
View Patent ↗An alkaline detergent for an automatic analyzer is disclosed, which is consisted of an alkaline solution containing polyoxyalkylene alkylether as a nonionic surfactant, and a cloud point-adjusting organic solvent.
1. An alkaline detergent for an automatic analyzer consisting of an alkaline solution containing polyoxyalkylene alkylether as a nonionic surfactant, and a cloud point-adjusting organic solvent,
wherein the nonionic surfactant comprises two kinds of alkylene groups differing in the number of carbon atoms.
2. The detergent according to claim 1 , wherein the nonionic surfactant is incorporated at a concentration ranging from 2%(v/v) to 10%(v/v).
3. The detergent according to claim 1 , wherein the nonionic surfactant comprises ethylene and propylene as alkylene moiety.
4. The detergent according to claim 1 , wherein the nonionic surfactant comprises lauryl ether as alkylether moiety.
5. The detergent according to claim 1 , wherein the cloud point-adjusting organic solvent is incorporated at a concentration ranging from 1%(v/v) to 10%(v/v).
6. The detergent according to claim 1 , wherein the cloud point-adjusting organic solvent is selected from primary alcohol having 1 to 3 carbon atoms and secondary alcohol having 1 to 3 carbon atoms.
7. A method of cleaning an automatic analyzer, which analyzer comprises:
a sampler for storing a test specimen;
a reagent reservoir for holding a reagent bottle storing a reagent;
a reaction disc for holding a reaction tube;
a mechanism for dispensing the test specimen and the reagent into the reaction tube;
a measurement section for measuring a reaction solution of the test specimen with the reagent; and
a cleaning section for cleaning the reaction tube;
the method comprising cleaning the reaction tube with an aqueous alkaline cleaning solution, an aqueous acidic cleaning solution and pure water, the aqueous alkaline cleaning solution comprising the alkaline detergent as claimed in claim 1 at a concentration of 1 to 3% by volume.
8. The cleaning method according to claim 7 , wherein the alkaline cleaning solution has a pH of 11 or more.
9. The cleaning method according to claim 7 , wherein the nonionic surfactant is incorporated in the alkaline detergent at a concentration ranging from 2%(v/v) to 10%(v/v).
10. The cleaning method according to claim 7 , wherein the nonionic surfactant incorporated in the alkaline detergent comprises ethylene and propylene as alkylene moiety.
11. The cleaning method according to claim 7 , wherein the nonionic surfactant incorporated in the alkaline detergent comprises lauryl ether as alkylether moiety.
12. The cleaning method according to claim 7 , wherein the cloud point-adjusting organic solvent is incorporated in the alkaline detergent at a concentration ranging from 1%(v/v) to 10%(v/v).
13. The cleaning method according to claim 7 , wherein the cloud point-adjusting organic solvent incorporated in the alkaline detergent is selected from primary alcohol having 1 to 3 carbon atoms and secondary alcohol having 1 to 3 carbon atoms.
14. An automatic analyzer comprising:
a sampler for storing a test specimen;
a reagent reservoir for holding a reagent bottle storing a reagent;
a reaction disc for holding a reaction tube;
a mechanism for dispensing the test specimen and the reagent into the reaction tube;
a measurement section for measuring a reaction solution of the test specimen with the reagent; and
a cleaning section for cleaning the reaction tube using an aqueous alkaline cleaning solution, an aqueous acidic cleaning solution and pure water;
wherein the aqueous alkaline cleaning solution contains the alkaline detergent of claim 1 at a concentration of 1 to 3% by volume.
15. The analyzer according to claim 14 , wherein the alkaline cleaning solution has a pH of 11 or more.
16. The analyzer according to claim 14 , wherein the nonionic surfactant incorporated in the alkaline detergent comprises ethylene and propylene as alkylene moiety.
17. The analyzer according to claim 14 , wherein the nonionic surfactant incorporated in the alkaline detergent comprises lauryl ether as alkylether moiety.
18. The analyzer according to claim 14 , wherein the cloud point-adjusting organic solvent incorporated in the alkaline detergent is selected from primary alcohol having 1 to 3 carbon atoms and secondary alcohol having 1 to 3 carbon atoms.
19. The method of claim 7 , wherein the aqueous alkaline cleaning solution consists of the alkaline detergent.
20. The analyzer according to claim 14 , wherein the aqueous alkaline cleaning solution consists of the alkaline detergent.