IP Library Granted Patent US 8,767,917
Granted Patent B2
US 8,767,917 · App. 11/459,074 · Granted Jul 1, 2014

System and method of delivering radiation therapy to a moving region of interest

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Quick Facts
Patent No.
US 8,767,917
App. No.
11/459,074
Granted
Jul 1, 2014
Kind
B2
Abstract

A system for and method of delivering radiation therapy to a moving region of interest is disclosed. The method, in one implementation, includes the acts of generating a plurality of treatment plans for providing radiation therapy, delivering radiation therapy to the patient following one of the plurality of treatment plans, monitoring the patient while providing radiation therapy, and changing the treatment plan based at least in part on monitoring the patient.

Claims (26)

1. A method of delivering radiation therapy to a patient when a region of interest is moving, the radiation therapy being delivered by a radiation therapy system including a multi-leaf collimator, the method comprising:

generating a treatment plan for delivering radiation therapy, the treatment plan including a series of machine instructions;

activating a radiation beam for delivering radiation therapy to the patient by following the treatment plan;

monitoring the patient while the radiation beam is active and delivering radiation to the patient; and

changing a leaf pattern of the multi-leaf collimator from the leaf pattern as specified by the treatment plan while the radiation beam is active based at least in part on the monitoring the patient,

wherein the changing a leaf pattern includes reordering the machine instructions.

2. A method as set forth in claim 1 wherein changing a leaf pattern further includes scaling the treatment plan.

3. A method as set forth in claim 1 wherein the changing a leaf pattern includes dynamically optimizing the treatment plan.

4. A method as set forth in claim 1 wherein the changing a leaf pattern is further based on dosimetric information.

5. A method as set forth in claim 4 wherein the dosimetric information comprises at least one of an accumulated dose for a current session and an accumulated dose for all sessions.

6. A method as set forth in claim 4 wherein the changing a leaf pattern includes performing deformation with the treatment plan.

7. A method of delivering radiation therapy to a patient when a region of interest is moving, the radiation therapy being delivered by a radiation therapy system, the method comprising:

generating a treatment plan for delivering radiation therapy, the treatment plan including a series of machine instructions for controlling a multi-leaf collimator;

activating a radiation beam for delivering radiation therapy to the patient by following the treatment plan;

monitoring the patient while the radiation beam is active and delivering radiation to the patient; and

changing a treatment parameter while the radiation beam is active and delivering radiation to the patient based at least in part on the monitoring the patient,

wherein the changing a treatment parameter includes changing a leaf pattern of the multi-leaf collimator and scaling at least one of the machine instructions.

8. A method as set forth in claim 7 wherein the changing a treatment parameter includes changing a treatment parameter different than the leaf pattern of the multi-leaf collimator.

9. A method as set forth in claim 8 wherein the treatment parameter includes changing a timing of the multi-leaf collimator.

10. A method as set forth in claim 7 wherein the radiation therapy is delivered by a radiation therapy system including a gantry, and wherein the changing a treatment parameter includes changing a gantry parameter.

11. A method as set forth in claim 10 wherein the gantry parameter includes at least one of a gantry speed and a gantry direction.

12. A method as set forth in claim 7 wherein the radiation therapy is delivered by a radiation therapy system including a patient support, and wherein the changing a treatment parameter includes changing a patient-support parameter.

13. A method as set forth in claim 12 wherein the patient-support parameter includes at least one of a patient-support speed and a patient-support direction.

14. A method as set forth in claim 7 wherein the radiation therapy is delivered by a radiation therapy system including a radiation module having a jaw, and wherein the changing a treatment parameter further includes changing a jaw parameter.

15. A method as set forth in claim 14 wherein the jaw parameter includes at least one of a jaw position and a jaw direction.

16. A method as set forth in claim 8 wherein changing a treatment parameter includes changing the leaf pattern of the multi-leaf collimator from the leaf pattern as specified by the treatment plan while the radiation beam is active based at least in part on the monitoring the patient, and wherein the series of machine instructions includes a set of leaf open times and wherein the changing a leaf pattern includes scaling at least one of the machine instructions.

Assignments (12)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 8, 2025
From: ACCURAY INCORPORATED
To: ACCURAY LLC
Reel/Frame 072189/0891 →
RELEASE OF SECURITY INTEREST Recorded Jun 6, 2025
From: FIRST-CITIZENS BANK & TRUST COMPANY
To: ACCURAY INCORPORATED
Reel/Frame 071638/0034 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 11, 2023
From: TOMOTHERAPY INCORPORATED
To: ACCURAY INCORPORATED
Reel/Frame 064218/0337 →
RELEASE OF SECURITY INTEREST Recorded May 20, 2021
From: MIDCAP FINANCIAL TRUST
To: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
Reel/Frame 056318/0751 →
RELEASE OF SECURITY INTEREST Recorded May 20, 2021
From: MIDCAP FUNDING IV TRUST (AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FUNDING X TRUST, AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FUNDING IV TRUST, AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FINANCIAL TRUST)
To: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
Reel/Frame 056318/0559 →
SECURITY INTEREST Recorded May 14, 2021
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: SILICON VALLEY BANK, AS ADMINISTRATIVE AND COLLATERAL AGENT
Reel/Frame 056247/0001 →
ASSIGNMENT OF SECURITY AGREEMENTS Recorded Mar 1, 2019
From: MIDCAP FUNDING X TRUST (AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FUNDING IV TRUST, AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FINANCIAL TRUST), AS EXISTING ADMINISTRATIVE AGENT
To: MIDCAP FUNDING IV TRUST, AS SUCCESSOR TO EXISTING ADMINISTRATIVE AGENT
Reel/Frame 048481/0804 →
SECURITY INTEREST Recorded Dec 19, 2017
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: MIDCAP FINANCIAL TRUST
Reel/Frame 044910/0685 →
SECURITY INTEREST Recorded Jun 15, 2017
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: MIDCAP FUNDING IV TRUST (AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FINANCIAL TRUST)
Reel/Frame 042826/0358 →
RELEASE OF SECURITY INTEREST Recorded Jun 15, 2017
From: CERBERUS BUSINESS FINANCE, LLC. AS COLLATERAL AGENT
To: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
Reel/Frame 042821/0580 →
ASSIGNMENT FOR SECURITY - PATENTS Recorded Jan 13, 2016
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: CERBERUS BUSINESS FINANCE, LLC, AS COLLATERAL AGENT
Reel/Frame 037513/0170 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 6, 2006
From: RUCHALA, KENNETH J.; OLIVERA, GUSTAVO H.; LU, WEIGUO; SCHNARR, ERIC; HUGHES, JOHN H.; KAPATOES, JEFFREY M.; MACKIE, THOMAS R.; RECKWERDT, PAUL J.
To: TOMOTHERAPY INCORPORATED
Reel/Frame 018486/0376 →