IP Library › Granted Patent US 7,790,453
Granted Patent B2
US 7,790,453 · App. 11/461,709 · Granted Sep 7, 2010

Smooth muscle progenitor cells

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Quick Facts
Patent No.
US 7,790,453
App. No.
11/461,709
Granted
Sep 7, 2010
Kind
B2
Abstract

Purified populations of smooth muscle progenitor cells are provided as well as methods of making and using the cells.

Claims (4)

1. An enriched population of blood-derived, adult smooth muscle progenitor cells, wherein said cells are isolated human cells, are positive for CD34, and lack exogenous nucleic acid.

2. The enriched population of adult smooth muscle progenitor cells of claim 1 , wherein said cells are positive for VEGF receptors.

3. The enriched population of adult smooth muscle progenitor cells of claim 2 , wherein said cells are positive for Flt1 and Flk receptor, and negative for the Tie-2 receptor, CD31, vWF, and VE-cadherin.

4. The enriched population of adult smooth muscle progenitor cells of claim 1 , wherein said cells are positive for a-actin, myosin heavy chain, and calponin.

Assignments (1)
CONFIRMATORY LICENSE Recorded Sep 5, 2008
From: MAYO FOUNDATION
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 021491/0325 →