Apparatus for producing tissue arrays
View Patent ↗An apparatus for producing a tissue array, having at least one donor block ( 2 ) that comprises tissue ( 3 ) to be investigated, is described. A marked tissue section of the tissue ( 3 ) to be investigated is arranged on a specimen slide ( 22 ), a hollow needle ( 5 ) for removing a sample from the tissue ( 3 ) being present. A sighting device ( 12 ) is provided for positioning the hollow needle ( 5 ) above the donor block ( 2 ).
1. An apparatus comprising:
a donor block including tissue to be investigate;
a specimen slide on which is provided a marked tissue section of the tissue to be investigated;
a hollow needle for removing a sample from the donor block;
a sighting device alignable with a marked site on the marked tissue section; and
a pantograph including a first scissor arm and a second scissor arm joined to one another, the first scissor arm being mechanically connected to the hollow needle, and the second scissor arm having the sighting device arranged thereon and carrying the sighting device above the specimen slide, wherein the pantograph positions the hollow needle relative to the donor block at a position corresponding to an alignment position of the sighting device relative to the marked tissue section.
2. The apparatus according to claim 1 , wherein the two scissor arms are rotatably joined to one another.
3. The apparatus according to claim 2 , wherein the second scissor arm includes a sight holder for holding the sighting device.
4. The apparatus according to claim 1 , further comprising a specimen slide holder for holding the specimen slide, wherein the sighting device is associated with the specimen slide holder.
5. The apparatus according to claim 1 , further comprising a turntable, wherein the donor block is arranged on the turntable.
6. The apparatus according to claim 4 , wherein the specimen slide holder is adjustably positionable above the donor block.
7. The apparatus according to claim 3 , further comprising a movable needle holder for holding the hollow needle and a punching lever for actuating the hollow needle, wherein the first scissor arm includes a receptacle for receiving the punching lever.
8. The apparatus according to claim 7 , wherein the needle holder is configured to hold a plurality of hollow needles in a circular arc, the plurality of hollow needles having different diameters.