IP Library Granted Patent US 7,630,849
Granted Patent B2
US 7,630,849 · App. 11/469,308 · Granted Dec 8, 2009

Method of automated calibration and diagnosis of laboratory instruments

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Quick Facts
Patent No.
US 7,630,849
App. No.
11/469,308
Granted
Dec 8, 2009
Kind
B2
Abstract

Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.

Claims (16)

1. A method for calibrating a laboratory instrument comprising,

providing a thermal cycling instrument adapted to image a multi-well plate;

providing a user with a set of predefined steps for performing at least one calibration test on the thermal cycling instrument, wherein before running the at least one calibration test, a user is prompted to install a multi-well plate into the instrument;

initiating the at least one calibration test, wherein the calibration test is run using the installed multi-well plate;

verifying the progress of the calibration test by applying at least one expert knowledge based test; and

informing the user of the status of the calibration test as a result of the at least one expert knowledge based test.

2. The method of claim 1 , wherein the multi-well plate contains fluorescent dyes.

3. The method of step 2 , wherein verifying the progress comprises applying at least one expert knowledge based test to verify that the correct multi-well plate was installed.

4. A computer storage medium containing instructions for performing method steps for calibrating a laboratory instrument, said method comprising,

providing a thermal cycling instrument adapted to image a multi-well plate;

providing a user with a set of predefined steps for performing at least one calibration test on the thermal cycling instrument, wherein before running the at least one calibration test, a user is prompted to install a multi-well plate into the instrument;

initiating the at least one calibration test, wherein the calibration test is run using the installed multi-well plate;

verifying the progress of the calibration test by applying at least one expert knowledge based test; and

informing the user the status of the calibration test as a result of the at least one expert knowledge based test.

5. The computer storage medium of claim 4 containing instructions for performing method steps for calibrating a laboratory instrument, wherein the multi-well plate contains fluorescent dyes.

6. The computer storage medium of claim 5 containing instructions for performing method steps for calibrating a laboratory instrument, wherein verifying the process comprises applying at least one expert knowledge based test to verify that the correct multi-well plate was installed.

Assignments (12)
CORRECTIVE ASSIGNMENT TO CORRECT THE RECEIVING PARTY NAME PREVIOUSLY RECORDED AT REEL: 030182 FRAME: 0677. ASSIGNOR(S) HEREBY CONFIRMS THE RELEASE OF SECURITY INTEREST. Recorded Mar 4, 2016
From: BANK OF AMERICA, N.A.
To: APPLIED BIOSYSTEMS, LLC
Reel/Frame 038006/0471 →
LIEN RELEASE Recorded Apr 9, 2013
From: BANK OF AMERICA, N.A.
To: APPLIED BIOSYSTEMS, INC.
Reel/Frame 030182/0677 →
MERGER Recorded Feb 26, 2010
From: APPLIED BIOSYSTEMS INC.
To: APPLIED BIOSYSTEMS, LLC
Reel/Frame 023994/0587 →
CHANGE OF NAME Recorded Feb 26, 2010
From: APPLERA CORPORATION
To: APPLIED BIOSYSTEMS INC.
Reel/Frame 023994/0538 →
CHANGE OF NAME Recorded Oct 14, 2009
From: APPLERA CORPORATION
To: APPLIED BIOSYSTEMS INC.
Reel/Frame 023371/0934 →
MERGER Recorded Oct 14, 2009
From: ATOM ACQUISITION CORPORATION
To: APPLIED BIOSYSTEMS INC.
Reel/Frame 023372/0097 →
MERGER Recorded Oct 14, 2009
From: ATOM ACQUISITION, LLC AND APPLIED BIOSYSTEMS INC.
To: APPLIED BIOSYSTEMS, LLC
Reel/Frame 023372/0136 →
MERGER Recorded Oct 7, 2009
From: ATOM ACQUISITION CORPORATION
To: APPLIED BIOSYSTEMS INC.
Reel/Frame 023341/0287 →
MERGER Recorded Oct 7, 2009
From: ATOM ACQUISITION, LLC AND APPLIED BIOSYSTEMS INC.
To: APPLIED BIOSYSTEMS, LLC
Reel/Frame 023341/0298 →
CHANGE OF NAME Recorded Oct 7, 2009
From: APPLERA CORPORATION
To: APPLIED BIOSYSTEMS INC.
Reel/Frame 023341/0269 →
SECURITY AGREEMENT Recorded Dec 5, 2008
From: APPLIED BIOSYSTEMS, LLC
To: BANK OF AMERICA, N.A, AS COLLATERAL AGENT
Reel/Frame 021976/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 15, 2007
From: DESIMAS, BRUCE E.; DOW, LESLIE A.
To: APPLERA CORPORATION
Reel/Frame 018758/0153 →