IP Library › Patent Application 11475568
Patent Application
App. No. 11/475,568

Cardiac muscle regeneration using mesenchymal stem cells

Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US None
App. No.
11/475,568
Abstract

Disclosed is a method for producing cardiomyocytes in vivo by administering to the heart of an individual a cardiomyocyte producing amount of mesenchymal stem cells. These cells can be administered as a liquid injectible or as a preparation of cells in a matrix which is or becomes solid or semi-solid. The cells can be genetically modified to enhance myocardial differentiation and integration. Also disclosed is a method for replacing cells ex vivo in a heart valve for implantation.

Claims (5)

1 - 53 . (canceled)

54 . A process for treating a patient with damaged heart muscle to improve heart function, comprising:

treating said patient to improve heart function by administering to said patient mesenchymal stem cells in an amount effective to improve heart function.

55 . The process of claim 54 wherein the mesenchymal stem cells are administered directly to the heart.

56 . The process of claim 55 wherein the mesenchymal stem cells are administered by injection.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 1, 2013
From: OSIRIS THERAPEUTICS, INC.
To: MESOBLAST INTERNATIONAL SÀRL
Reel/Frame 031533/0828 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INVENTOR ALASTAIR MORGAN MACKAY'S NAME, PREVIOUSLY RECORDED A REEL 021049 FRAME 0188. Recorded Jul 14, 2008
From: PITTENGER, MARK F.; GORDON, STEPHEN L.; MACKAY, ALASTAIR MORGAN; MARTIN, BRADLEY J.
To: OSIRIS THERAPEUTICS, INC.
Reel/Frame 021239/0091 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 5, 2008
From: PITTENGER, MARK F.; GORDON, STEPHEN L.; MACKAY, ALASTAIR MORGAR; MARTIN, BRADLEY J.
To: OSIRIS THERAPEUTICS, INC.
Reel/Frame 021049/0188 →