N-substituted piperazines
View Patent ↗Novel N-alkyl substituted piperazines have been discovered, which are useful as insecticides or fungicides. Such compounds are of Formula (I) wherein X, Y, R1 and R2 are as defined herein.
1. A compound of the Formula (I)
wherein
X and Y are each independently selected from the group consisting of a direct bond, alkyl, carbonyl, carbonylalkyl, carbonylalkylether, carboxylalkyl, alkylcarbonyl, alkylcarboxyl, and alkylether;
with the proviso that both X and Y cannot be a direct bond; and when
either X or Y is a direct bond, then the R1 or R2 associated with that bond is not phenyl or optionally substituted phenyl; and
R1 and R2 are each independently selected from the group consisting of:
alkyl;
aryl, optionally substituted with cyano, alkoxy, halogen, alkylhalo, alkoxyhalo, carboxylalkyl, carbonylalkyl, benzyloxy, nitro, benzoyl, phenyl, carboxamido, or heteroaryl;
heteroaryl, optionally substituted with aryl, heteroaryl, alkyl, halogen, alkylhalo, alkoxy, cycloalkyl or cyano;
cycloalkyl, optionally substituted with alkyl or halogen; and
a heterocyclic ring, optionally substituted with alkyl.
2. The compound of claim 1 wherein X and Y are each independently selected from the group consisting of a direct bond, alkyl, and carbonyl.
3. The compound of claim 2 wherein R1 and R2 are each independently selected from the group consisting of:
alkyl;
aryl, optionally substituted with cyano, alkoxy, halogen, alkylhalo, alkoxyhalo, carboxylalkyl, carbonylalkyl, benzyloxy, nitro, benzoyl, phenyl, carboxamido, or heteroaryl; and
heteroaryl, optionally substituted with aryl, heteroaryl, alkyl, halogen, alkylhalo, alkoxy, cycloalkyl or cyano.
4. An insecticidal or fungicidal composition comprising the compound of claim 1 and a phytologically acceptable carrier.
5. A method of controlling insects comprising applying to a locus where control is desired an insect-inactivating amount of a compound of claim 1 .
6. A method for controlling fungal attack comprising applying to the soil, plant, roots, foliage, seed or locus of the fungus, or to a locus in which the infestation is to be controlled, a fungicidal effective amount of the compound of claim 1 .