Metal carnitine chelates
View Patent ↗Metal carnitine chelates comprising carnitine chelated to a nutritionally relevant metal can be used for general nutrition as well as well as to treat a variety of health related problems and symptoms. For example, metal carnitine chelates can be used to maintain good cardiovascular health, increase male fertility, enhance weight loss, provide mineral and/or carnitine supplements for mineral- and/or carnitine-deficient subjects, and reduce alcohol dependency and associated symptoms. Nutritionally relevant metals that can be used include copper, zinc, magnesium, calcium, iron, chromium, and manganese, to name a few.
1. A metal carnitine chelate, comprising carnitine chelated to a nutritionally relevant metal at a 1:1 to 4:1 molar ratio.
2. A metal carnitine chelate as in claim 1 , wherein the metal is copper.
3. A metal carnitine chelate as in claim 1 , wherein the metal is zinc.
4. A metal carnitine chelate as in claim 1 , wherein the metal is manganese.
5. A metal carnitine chelate as in claim 1 , wherein the metal is magnesium.
6. A metal carnitine chelate as in claim 1 , wherein the metal is calcium.
7. A metal carnitine chelate as in claim 1 , wherein the metal is iron.
8. A metal carnitine chelate as in claim 1 , wherein the metal is chromium.
9. A metal carnitine chelate as in claim 1 , wherein the metal is vanadium.
10. A metal carnitine chelate as in claim 1 , wherein the carnitine to metal molar ratio is about 1:1.
11. A metal carnitine chelate as in claim 1 , wherein the carnitine to metal molar ratio is about 2:1.
12. A composition for delivering a mineral and carnitine to a subject, comprising:
a metal carnitine chelate including carnitine chelated to and a nutritionally relevant metal at a 1:1 to 4:1 molar ratio; and
a carrier.
13. A composition as in claim 12 , wherein the metal is selected from the group consisting of copper, zinc, manganese, magnesium, calcium, iron, vanadium, and chromium.
14. A composition as in claim 12 , wherein the carnitine to metal molar ratio is about 1:1.
15. A composition as in claim 12 , wherein the carnitine to metal molar ratio is about 2:1.
16. A composition as in claim 12 , further including a therapeutically effective agent other than the metal carnitine chelate.
17. A composition as in claim 16 , wherein the therapeutically effective agent is selected from the group consisting of a drug, a vitamin, an enzyme, an herb, and combinations thereof.
18. A composition as in claim 16 , wherein the therapeutically effective agent is selected from the group consisting of a metal salt, a metal amino acid chelate, a second metal carnitine chelate, and combinations thereof.
19. A composition as in claim 12 , wherein the composition is in a liquid dosage form.
20. A composition as in claim 12 , wherein the composition is in a solid dosage form.
21. A composition as in claim 20 , wherein the composition is in powder form.
22. A composition as in claim 20 , wherein the solid dosage form is incorporated into a tablet or capsule.
23. A composition as in claim 12 , wherein the carrier includes maltodextrin, rice flour, wheat starch, potato strarch, corn starch, tapioca starch, rice starch, cacia gum, fumed silica, or combinations thereof.
24. A method of providing a nutritional or therapeutic effect in a subject, comprising administering a metal carnitine chelate to a subject, said metal carnitine chelate including carnitine chelated to a nutritionally relevant metal at a 1:1 to 4:1 molar ratio.
25. A method as in claim 24 , wherein the metal is selected from the group consisting of copper, zinc, manganese, magnesium, calcium, iron, vanadium, and chromium.
26. A method as in claim 24 , wherein the carnitine to metal molar ratio is about 1:1.
27. A method as in claim 24 , wherein the carnitine to metal molar ratio is about 2:1.
28. A method as in claim 24 , wherein the therapeutic effect includes enhancement of an ability of the subject to exercise, and the step of administering occurs prior within an hour prior to exercising.
29. A method as in claim 28 , wherein the metal is selected from the group consisting of copper, zinc, magnesium, manganese, and combinations thereof.
30. A method as in claim 24 , wherein the therapeutic effect includes improved cardiovascular health for the subject.
31. A method as in claim 30 , wherein the metal is selected from the group consisting of calcium, magnesium, zinc, copper, and combinations thereof.
32. A method as in claim 24 , wherein the therapeutic effect includes enhancing weight loss performance in the subject.
33. A method as in claim 32 , wherein the metal is selected from the group consisting of calcium, zinc, magnesium, manganese, chromium, vanadium, and combinations thereof.
34. A method as in claim 24 , wherein the therapeutic effect includes improving male fertility.
35. A method as in claim 34 , wherein the metal is selected from the group consisting of calcium, zinc, magnesium, manganese, and combinations thereof.
36. A method as in claim 24 , wherein the therapeutic effect includes enhancing carnitine levels in the blood and tissue of the subject.
37. A method as in claim 36 , wherein the subject is carnitine deficient.
38. A method as in claim 24 , wherein the therapeutic effect includes enhancing mineral levels in the blood and tissue of the subject.
39. A method as in claim 38 , wherein the subject is deficient of a specific mineral present in the metal carnitine chelate.
40. A method as in claim 24 , wherein the therapeutic effect includes reducing symptoms of alcohol desire or dependency in a human subject.
41. A method as in claim 40 , wherein the metal is selected from the group consisting of copper, zinc, manganese, and combinations thereof.
42. A method as in claim 24 , further comprising co-administering a therapeutically effective agent other than the metal carnitine chelate.
43. A method as in claim 42 , wherein the therapeutically effective agent is a second metal carnitine chelate that includes a different metal than the metal carnitine chelate.
44. A method as in claim 42 , wherein the therapeutically effective agent is selected from the group consisting of a drug, a vitamin, an enzyme, and combinations thereof.
45. A method as in claim 42 , wherein the therapeutically effective agent is selected from the group consisting of a metal salt, a metal amino acid chelate, and combinations thereof.