Kits for treating dysfunction of cardiac muscle
View Patent ↗Kits are described for the treatment of acute or chronic dysfunction of cardiac muscle. The kit includes a platelet-rich plasma composition with a pH adjusting agent and a catheter or syringe for delivery of the platelet-rich plasma composition to dysfunctional cardiac muscle. The kit may also include a syringe for withdrawing blood from a patient and a centrifuge device to obtain platelet-rich plasma.
1. A delivery system for treating acute or chronic dysfunction of cardiac muscle comprising:
a platelet-rich plasma composition comprising platelet-rich plasma and a pH adjusting agent; and
a catheter for delivery of the platelet-rich plasma composition to dysfunctional cardiac muscle,
wherein the platelet-rich plasma composition does not contain an activator of the platelet-rich plasma.
2. The delivery system of claim 1 , wherein the pH adjusting agent provides a pH of about 7.3 to 7.5.
3. The delivery system of claim 1 , wherein the pH adjusting agent is a bicarbonate buffer.
4. The delivery system of claim 1 , wherein a plasma used for the platelet-rich plasma is from an autologous source.
5. The delivery system of claim 1 , further comprising an implantable device.
6. The delivery system of claim 5 , wherein the implantable device is a stent.
7. A kit for treating acute or chronic dysfunction of cardiac muscle comprising:
a syringe for withdrawing blood from a patient;
a centrifuge device to obtain platelet-rich plasma;
a pH adjusting agent for the platelet-rich plasma to provide a platelet-rich composition having a pH of about 7.3 to 7.5; and
a catheter for delivery of the platelet-rich plasma composition to dysfunctional cardiac muscle,
wherein the kit does not contain an activator of the platelet-rich plasma.
8. The kit of claim 7 , wherein the pH adjusting agent is a bicarbonate buffer.