IP Library › Granted Patent US 7,883,695
Granted Patent B2
US 7,883,695 · App. 11/503,324 · Granted Feb 8, 2011

IL-12P40 and IL-B30 polypeptide complex

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Quick Facts
Patent No.
US 7,883,695
App. No.
11/503,324
Granted
Feb 8, 2011
Kind
B2
Abstract

Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.

Claims (8)

1. A composition comprising an IL-12 p40 polypeptide and an IL-B30 polypeptide, wherein:

a) the IL-12 p40 polypeptide comprises a sequence that is at least 95% identical to the mature sequence of SEQ ID NO:20; and

b) the IL-B30 polypeptide comprises a sequence that is at least 95% identical to the mature sequence of SEQ ID NO:2,

wherein the two polypeptides form a complex that induces proliferation of memory T cells.

2. The composition of claim 1 , wherein:

a) the IL-12 p40 polypeptide comprises the mature sequence of SEQ ID NO:20; and

b) the IL-B30 polypeptide comprises the mature sequence of SEQ ID NO:2.

3. The composition of claim 1 , further comprising a pharmaceutically acceptable carrier.

Assignments (1)
CHANGE OF NAME Recorded Aug 30, 2012
From: SCHERING CORPORATION
To: MERCK SHARP & DOHME CORP.
Reel/Frame 028884/0151 →