Active aromatic sulfonamide organic compounds and biocidal uses thereof
View Patent ↗A biocidal solution comprising aromatic N-halosulfonamide organic compounds and methods of using the biocidal solution are disclosed. The solution may further comprise a wetting agent, a low molecular weight alcohol, and buffering agents. The biocidal solution is used to arrest or kill unwanted organisms.
1. A process for killing unwanted microorganisms on an affected area, comprising:
contacting the area with a biocidal solution comprising an effective amount of a halo active aromatic sulfonamide compound of the following Formula I:
wherein
X is a halogen;
R 3 is methyl or COOM;
R 1 , R 2 , R 4 , and R 5 are independently selected from hydrogen, CF 3 , COOH, an ester or alkylated amide, COOM, CN, NO 2 , SO 3 H, a halogen, a substituted or unsubstituted phenyl group, a sulfonamide, a halosulfonamide, and a straight or branched aliphatic moiety from C 1 to C 12 , wherein the same straight or branched aliphatic moiety may be substituted at one or more of the aliphatic hydrogens;
at least one of R 1 , R 2 , R 4 and R 5 is not hydrogen; and
M is an alkali or alkaline earth metal.
2. The process of claim 1 , wherein the solution further comprises a wetting agent that essentially does not react with the sulfonamide compound.
3. The process of claim 2 , where the wetting agent is a nonionic wetting agent.
4. The process of claim 2 , wherein the concentration of the wetting agent in the biocidal solution is from about 0.05 to about 5%.
5. The process of claim 1 , wherein the solution further comprises a low molecular weight alcohol.
6. The process of claim 5 , wherein the alcohol is selected from methanol and t-butanol.
7. The process of claim 5 , wherein the concentration of the alcohol in the biocidal solution is from about 0.1 to about 5.0%.
8. The process of claim 1 , wherein the solution is buffered to a pH of from about 6.5 to about 10.0.
9. The process of claim 8 , wherein the solution is buffered to a pH of from about 7.0 to about 9.0.
10. The process of claim 9 , wherein the solution is buffered to a pH of from about 7.5 to about 8.5.
11. The process of claim 8 , wherein the solution is buffered with sodium bicarbonate.
12. The process of claim 1 , wherein the concentration of the sulfonamide compound in the biocidal solution is from about 0.1 to about 37%.
13. The process of claim 12 , wherein the concentration of the sulfonamide compound in the biocidal solution is from about 0.1 to about 20%.
14. The process of claim 1 , wherein the biocidal solution is incorporated into a soap, lotion, wipe, or swab which is then contacted with the affected area.
15. A process for killing unwanted microorganisms on an affected area, comprising: contacting the area with a biocidal solution comprising an effective amount of an N-halo-4-carboxybenzene sulfonamide of the following Formula V:
wherein X is a halogen; and
M is an alkali or alkaline earth metal.
16. The process of claim 15 , wherein the sulfonamide compound is of the following Formula VI:
17. The process of claim 15 , wherein the sulfonamide compound is of the following Formula VII:
18. A process for killing unwanted microorganisms on an affected area, comprising contacting the area with a biocidal solution, wherein the solution comprises
an effective amount of a halo active aromatic sulfonamide compound of the following Formula V:
wherein X is a halogen; and M is an alkali or alkaline earth metal;
a wetting agent; and
an alcohol selected from methanol and t-butanol.
19. The process of claim 18 , wherein the solution is buffered to a pH of from about 7.5 to about 8.5.