IP Library Granted Patent US 8,795,720
Granted Patent B2
US 8,795,720 · App. 11/511,808 · Granted Aug 5, 2014

Liquid filled delivery system

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Quick Facts
Patent No.
US 8,795,720
App. No.
11/511,808
Granted
Aug 5, 2014
Kind
B2
Abstract

The present invention provides a delivery system comprising: (a) a container which is a formed body obtained from a film forming composition comprising at least one polysaccharide or polysaccharide derivative; (b) a liquid fill comprising a matrix composition of at least one solvent which is both polar and hygroscopic or a mixture of solvents each of which is both polar and hygroscopic; and (c) an active agent or a mixture of active agents wherein the active agent is soluble in said polar and hygroscopic solvent or mixture of polar and hygroscopic solvents, and a process for the preparation of said delivery system.

Claims (7)

1. A delivery system comprising: (a) a hard capsule comprising hydroxypropylmethyl cellulose (HPMC); (b) a liquid fill comprising at least one solvent which is both polar and hygroscopic or a mixture of solvents each of which is both polar and hygroscopic, wherein at least one solvent is glycerol; and (c) an active agent or a mixture of active agents, wherein the active agent is solubilized in said polar and hygroscopic solvent or mixture of polar and hygroscopic solvents.

2. The delivery system according to claim 1 , wherein the system further comprises water.

3. The delivery system according to claim 1 , further comprising at least one coating.

4. The delivery system according to claim 1 , wherein the active agent is selected from the group consisting of dietary supplements, pharmaceuticals, amino acids, vitamins, and herbals.

5. The delivery system according to claim 4 , wherein the dietary supplement is selected from the group consisting of calcium supplements, mineral supplements, garlic, ginseng, ginkgo biloba, Echinacea purpurea, Echinacea angustifolia, St John's wort, royal jelly, artichoke, aloe vera, red clover, Carnitine, L-Carnitine, L-Carnitine acetyl, L-Carnitine Tartrate, L-Carnitine hydrochloride, S-Adenosyl methionine (SAM-e), S-adenosyl methionin tosylate, a combination of glycosamine and chondroitine, and a combination of a salt of glycosamine and chondroitine.

6. The delivery system according to claim 1 , wherein the liquid fill further optionally comprises at least one coloring agent in an amount ranging from about 0% to about 10% based upon the weight of the liquid.

7. The delivery system according to claim 5 , further comprising at least one coating.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Jul 10, 2017
From: UBS AG, STAMFORD BRANCH
To: CAPSUGEL BELGIUM BVBA
Reel/Frame 043136/0353 →
CORRECTIVE ASSIGNMENT TO CORRECT THE NAME OF ASSIGNEE PREVIOUSLY RECORDED ON REEL 027439 FRAME 0097. ASSIGNOR(S) HEREBY CONFIRMS THE CHANGE OF NAME FROM CAPSUGEL BELGIUM TO CAPSUGEL BELGIUM NV. Recorded Dec 4, 2012
From: CAPSUGEL BELGIUM
To: CAPSUGEL BELGIUM NV
Reel/Frame 029426/0077 →
CHANGE OF NAME Recorded Dec 23, 2011
From: CAPSUGEL BELGIUM BVBA
To: CAPSUGEL BELGIUM
Reel/Frame 027439/0097 →
SECURITY AGREEMENT Recorded Aug 29, 2011
From: CAPSUGEL BELGIUM BVBA
To: UBS AG, STAMFORD BRANCH, AS COLLATERAL AGENT
Reel/Frame 026820/0766 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 24, 2011
From: WARNER-LAMBERT COMPANY LLC
To: CAPSUGEL BELGIUM BVBA
Reel/Frame 026797/0867 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 2, 2006
From: MADIT, NICOLAS
To: WARNER-LAMBERT COMPANY LLC
Reel/Frame 018377/0605 →